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KLRK1

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. This gene encodes a member of the NKG2 family. The encoded transmembrane protein is characterized by a type II membrane orientation (has an extracellular C terminus) and the presence of a C-type lectin domain. It binds to a diverse family of ligands that include MHC class I chain-related A and B proteins and UL-16 binding proteins, where ligand-receptor interactions can result in the activation of NK and T cells. The surface expression of these ligands is important for the recognition of stressed cells by the immune system, and thus this protein and its ligands are therapeutic targets for the treatment of immune diseases and cancers. Read-through transcription exists between this gene and the upstream KLRC4 (killer cell lectin-like receptor subfamily C, member 4) family member in the same cluster.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-YY2584 Anti-KLRK1 (CBYY-C0357) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBYY-C0357 Mouse scfv-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-YY2951 Anti-KLRK1 (CBYY-C0357) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBYY-C0357 Mouse scfv-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-CQ7090 Anti-KLRK1 (BAT221) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Non-Human Primate BAT221 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ7120 Anti-KLRK1 (CBXC-1951) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXC-1951 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ7600 Anti-KLRK1 (CBXC-1951) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human CBXC-1951 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1122-LX231 Anti-KLRK1 (X11X231) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human X11X231 Mouse scFv-CD28-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1122-LX232 Anti-KLRK1 (X11X232) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human X11X232 Mouse scFv-CD28-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1122-LX233 Anti-KLRK1 (X11X233) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human X11X233 Mouse scFv-CD28-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1122-LX234 Anti-KLRK1 (X11X234) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human X11X234 Mouse scFv-CD28-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1122-LX235 Anti-KLRK1 (X11X235) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human X11X235 Mouse scFv-CD28-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1122-LX629 Anti-KLRK1 (X11X231) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Human X11X231 Mouse scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1122-LX630 Anti-KLRK1 (X11X232) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Human X11X232 Mouse scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1122-LX631 Anti-KLRK1 (X11X233) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Human X11X233 Mouse scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1122-LX632 Anti-KLRK1 (X11X234) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Human X11X234 Mouse scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1122-LX633 Anti-KLRK1 (X11X235) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Human X11X235 Mouse scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1122-LX1027 Anti-KLRK1 (X11X231) h(ICOS-4-1BB-CD3ζ) CAR, pCDCAR1 Human X11X231 Mouse scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1122-LX1028 Anti-KLRK1 (X11X232) h(ICOS-4-1BB-CD3ζ) CAR, pCDCAR1 Human X11X232 Mouse scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1122-LX1029 Anti-KLRK1 (X11X233) h(ICOS-4-1BB-CD3ζ) CAR, pCDCAR1 Human X11X233 Mouse scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1122-LX1030 Anti-KLRK1 (X11X234) h(ICOS-4-1BB-CD3ζ) CAR, pCDCAR1 Human X11X234 Mouse scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1122-LX1031 Anti-KLRK1 (X11X235) h(ICOS-4-1BB-CD3ζ) CAR, pCDCAR1 Human X11X235 Mouse scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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