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Epstein-Barr virus (EBV) latent membrane protein 2 (LMP2) are two viral proteins of the Epstein–Barr virus. LMP2A/LMP2B are transmembrane proteins that act to block tyrosine kinase signaling. LMP2A is a transmembrane protein that inhibits normal B-cell signal transduction by mimicking an activated B-cell receptor (BCR). The N-terminus domain of LMP2A is tyrosine phosphorylated and associates with Src family protein tyrosine kinases (PTKs) as well as spleen tyrosine kinase (Syk). PTKs and Syk are associated with BCR signal transduction.
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| CAT | Product Name | Target Species | TCR Clone | Host Species | Epitope | Allele | Vector Type | Inquiry & Datasheet |
| TCR-L015 | Human anti-LMP2 (FLRGRAYGL) T Cell Receptor, pMP71 | EBV | Human | FLRGRAYGL | HLA-B8 | retroviral vector | ||
| TCR-L056 | Human anti-LMP2 (CLGGLLWT) T Cell Receptor, pSFG | EBV | Human | CLGGLLWT | HLA-A2 | retroviral vector | ||
| TCR-L057 | Human anti-LMP2 (CLGGLLTMV) T Cell Receptor, pMP71 | EBV | Human | CLGGLLTMV | HLA-A0201 | retroviral vector | ||
| TCR-L055Z | Human anti-LMP2 (CLGGLLWT) T cell receptor, pCDTCR1 | EBV | Human | CLGGLLWT | HLA-A2 | Lentiviral | ||
| TCR-L056Z | Human anti-LMP2 (CLGGLLMW) T cell receptor, pCDTCR1 | EBV | Human | CLGGLLTMV | HLA-A0201 | Lentiviral | ||
| TCR-C108Z | Human anti-LMP2 T cell receptor (8), pCDTCR1 | EBV | 8 | Human | RRRWRRLTV | HLA-B*2709 | Lentiviral | |
| TCR-C109Z | Human anti-LMP2 T cell receptor (NB20), pCDTCR1 | EBV | NB20 | Human | CLGGLLTMV | HLA-A2 | Lentiviral | |
| TCR-C110Z | Human anti-LMP2 T cell receptor (PL5.05), pCDTCR1 | EBV | PL5.05 | Human | CLGGLLTMV | HLA-A2 | Lentiviral | |
| TCR-C111Z | Human anti-LMP2 T cell receptor (PL5.04), pCDTCR1 | EBV | PL5.04 | Human | LLWTLVLL | HLA-A2 | Lentiviral | |
| TCR-C112Z | Murinized anti-LMP2 T cell receptor, pCDTCR1 | EBV | Murinized | CLGGLLTMV | HLA-A2 | Lentiviral | ||
| TCR-L323 | Human anti-latent membrane protein 2 LMP-2 T cell receptor, pCDTCR1 | EBV | Human | CLGGLLTMV | HLA-A0201 | Lentiviral | ||
| TCR-YC0631 | Human anti-LMP2 T cell receptor ((NB20)-1), pCDTCR1 | NB20 | Human | ALGGLLTMV | HLA-A*02:01 | Lentiviral vector | ||
| TCR-YC0632 | Human anti-LMP2 T cell receptor ((NB20)-2), pCDTCR1 | NB20 | Human | CLAGLLTMV | HLA-A*02:01 | Lentiviral vector | ||
| TCR-YC0633 | Human anti-LMP2 T cell receptor ((NB20)-3), pCDTCR1 | NB20 | Human | CLGALLTMV | HLA-A*02:01 | Lentiviral vector | ||
| TCR-YC0634 | Human anti-LMP2 T cell receptor ((NB20)-4), pCDTCR1 | NB20 | Human | CLGGLATMV | HLA-A*02:01 | Lentiviral vector | ||
| TCR-YC0635 | Human anti-LMP2 T cell receptor ((NB20)-5), pCDTCR1 | NB20 | Human | CLGGLLAMV | HLA-A*02:01 | Lentiviral vector |
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CellRapeutics™ In Vivo Cell Engineering: One-stop in vivo T/B/NK cell and macrophage engineering services covering vectors construction to function verification.
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