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This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. At least four variants encoding the same protein have been found for this gene.
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| CAT | Product Name | Target Species | Antibody Clone | Antibody Host | Receptor Construction | Vector Type | Targeting Cell Type | CAR Vector Type | Inquiry & Datasheet |
| CAR-SB-LX0327 | Anti-MAGE-A4 (CB-P35) h(CD28-CD3ζ) CAR, pSBCAR1 | Human | CB-P35 | Mouse | scFv-CD28-CD3ζ | Sleeping Beauty (SB) transposon | T cell | ||
| XS-0822-YF635 | Anti-Human MAGE-A4 (XW-635) h(41BB-CD3ζ) CAR IVT Plasmid, pCARIVT | Human | XW-635 | Mouse | scFv-41BB-CD3ζ | In Vitro Transcription (IVT) Vector | |||
| XS-0822-YF636 | Anti-Mouse MAGE-A4 (XW-636) m(41BB-CD3ζ) CAR IVT Plasmid, pCARIVT | Mouse | XW-636 | Rat | scFv-41BB-CD3ζ | In Vitro Transcription (IVT) Vector | |||
| XS-0822-YF1555 | Anti-Human MAGE-A4 (XW-635) h(CD28-CD3ζ) CAR IVT Plasmid, pCARIVT | Human | XW-635 | Mouse | scFv-CD28-CD3ζ | In Vitro Transcription (IVT) Vector | |||
| XS-0822-YF1556 | Anti-Mouse MAGE-A4 (XW-636) m(CD28-CD3ζ) CAR IVT Plasmid, pCARIVT | Mouse | XW-636 | Rat | scFv-CD28-CD3ζ | In Vitro Transcription (IVT) Vector | |||
| XS-0822-YF2475 | Anti-Human MAGE-A4 (XW-635) h(CD28-41BB-CD3ζ) CAR IVT Plasmid, pCARIVT | Human | XW-635 | Mouse | scFv-CD28-41BB-CD3ζ | In Vitro Transcription (IVT) Vector | |||
| XS-0822-YF2476 | Anti-Mouse MAGE-A4 (XW-636) m(CD28-41BB-CD3ζ) CAR IVT Plasmid, pCARIVT | Mouse | XW-636 | Rat | scFv-CD28-41BB-CD3ζ | In Vitro Transcription (IVT) Vector | |||
| XS-0822-YF8562 | TS-Fluc Anti-Human MAGE-A4 scFv (XW-635) CD28-CD3ζ CAR, pCDCAR1 | Human | XW-635 | Mouse | 7H-YB-Fluc-EF1a-scFv-CD28-CD3ζ | Lentiviral vector | |||
| XS-0822-YF8563 | TS-Fluc Anti-Mouse MAGE-A4 scFv (XW-636) CD28-CD3ζ CAR, pCDCAR1 | Mouse | XW-636 | Rat | 7H-YB-Fluc-EF1a-scFv-CD28-CD3ζ | Lentiviral vector | |||
| XS-0822-YF8971 | TS-Fluc Anti-Human MAGE-A4 scFv (XW-635) 41BB-CD3ζ CAR, pCDCAR1 | Human | XW-635 | Mouse | 7H-YB-Fluc-EF1a-scFv-41BB-CD3ζ | Lentiviral vector | |||
| XS-0822-YF8972 | TS-Fluc Anti-Mouse MAGE-A4 scFv (XW-636) 41BB-CD3ζ CAR, pCDCAR1 | Mouse | XW-636 | Rat | 7H-YB-Fluc-EF1a-scFv-41BB-CD3ζ | Lentiviral vector | |||
| XS-0822-YF9380 | TS-Fluc Anti-Human MAGE-A4 scFv (XW-635) CD28-41BB-CD3ζ CAR, pCDCAR1 | Human | XW-635 | Mouse | 7H-YB-Fluc-EF1a-scFv-CD28-41BB-CD3ζ | Lentiviral vector | |||
| XS-0822-YF9381 | TS-Fluc Anti-Mouse MAGE-A4 scFv (XW-636) CD28-41BB-CD3ζ CAR, pCDCAR1 | Mouse | XW-636 | Rat | 7H-YB-Fluc-EF1a-scFv-CD28-41BB-CD3ζ | Lentiviral vector | |||
| XS-0822-YF9789 | TS-IL15 SA Anti-Human MAGE-A4 scFv (XW-635) CD28-CD3ζ CAR, pCDCAR1 | Human | XW-635 | Mouse | 7H-YB-IL15 SA-EF1a-scFv-CD28-CD3ζ | Lentiviral vector | |||
| XS-0822-YF9790 | TS-IL15 SA Anti-Mouse MAGE-A4 scFv (XW-636) CD28-CD3ζ CAR, pCDCAR1 | Mouse | XW-636 | Rat | 7H-YB-IL15 SA-EF1a-scFv-CD28-CD3ζ | Lentiviral vector | |||
| XS-0822-YF10198 | TS-IL15 SA Anti-Human MAGE-A4 scFv (XW-635) 41BB-CD3ζ CAR, pCDCAR1 | Human | XW-635 | Mouse | 7H-YB-IL15 SA-EF1a-scFv-41BB-CD3ζ | Lentiviral vector | |||
| XS-0822-YF10199 | TS-IL15 SA Anti-Mouse MAGE-A4 scFv (XW-636) 41BB-CD3ζ CAR, pCDCAR1 | Mouse | XW-636 | Rat | 7H-YB-IL15 SA-EF1a-scFv-41BB-CD3ζ | Lentiviral vector | |||
| XS-0822-YF10608 | TS-IL15 SA Anti-Mouse MAGE-A4 scFv (XW-636) CD28-41BB-CD3ζ CAR, pCDCAR1 | Mouse | XW-636 | Rat | 7H-YB-IL15 SA-EF1a-scFv-CD28-41BB-CD3ζ | Lentiviral vector | |||
| XS-0123-ZP549 | Anti-MAGE-A4 (CB-P34) h(scFv-CD3ε) TRuC, pCDTRC1 | Mouse | CB-P34 | Rat | scFv-CD3ε | Lentiviral vector | T cell |
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