MSLN

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-YF017 Anti-MSLN (CBL-YF01) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human CBL-YF001 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF018 Anti-MSLN (CBL-YF01) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBL-YF001 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF056 Anti-MSLN (CBL-YF013) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human CBL-YF013 Humanized scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF057 Anti-MSLN (CBL-YF013) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBL-YF013 Humanized scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP8482 A uniCAR [Anti-biotin-dimeric avidin CAR], with a scFv-based CAR Adaptor [Anti-MSLN], a Switchable CAR System Ovarian cancer Lentiviral vector   Add to Cart   Datasheet
CAR-ZP8501 A uniCAR [Anti-leucine zipper CAR], with a mAb-based CAR Adaptor [Anti-MSLN], a Switchable CAR System Ovarian cancer Lentiviral vector   Add to Cart   Datasheet
CARP-LX-084 Anti-MSLN h(BBζ) CART, Combined with R59022, a CAR Plus System Human 41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
CARP-LX-085 Anti-MSLN h(BBζ) CART, Combined with R59949, a CAR Plus System Human 41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
CARP-LX-086 Anti-MSLN h(BBζ) CART, Combined with Sch-58261, a CAR Plus System Human P4 0 41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0722-YF289 TS-IL15 SA Anti-Human MSLN scFv (m912) 4-1BB-CD3ζ CAR, pCDCAR1 Human m912 Human 7H-YB-IL15 SA-EF1a-scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-YF290 TS-IL15 SA Anti-Human MSLN scFv (CBL-YF049) 4-1BB-CD3ζ CAR, pCDCAR1 Human CBL-YF049 Humanized 7H-YB-IL15 SA-EF1a-scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-YF291 TS-IL15 SA Anti-Human MSLN scFv (M5) 4-1BB-CD3ζ CAR, pCDCAR1 Human M5 Human 7H-YB-IL15 SA-EF1a-scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-YF350 TS-IL15 SA Anti-Human MSLN scFv (CBL-YF049) CD28-4-1BB-CD3ζ CAR, pCDCAR1 Human CBL-YF049 Humanized 7H-YB-IL15 SA-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-YF351 TS-IL15 SA Anti-Human MSLN scFv (M5) CD28-4-1BB-CD3ζ CAR, pCDCAR1 Human M5 Human 7H-YB-IL15 SA-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-YF410 TS-NKG2DL Anti-hCD3 and Anti-Human MSLN scFv (CBL-YF049) CD28-CD3ζ CAR, pCDCAR1 Human CBL-YF049 Humanized 7H-YB-NKG2DL Anti-hCD3 and (OKT3 scFv-NKG2D ECD)-EF1a-scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-YF411 TS-NKG2DL Anti-hCD3 and Anti-Human MSLN scFv (M5) CD28-CD3ζ CAR, pCDCAR1 Human M5 Human 7H-YB-NKG2DL Anti-hCD3 and (OKT3 scFv-NKG2D ECD)-EF1a-scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-YF469 TS-NKG2DL Anti-hCD3 and Anti-Human MSLN scFv (m912) 4-1BB-CD3ζ CAR, pCDCAR1 Human m912 Human 7H-YB-NKG2DL Anti-hCD3 and (OKT3 scFv-NKG2D ECD)-EF1a-scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-YF470 TS-NKG2DL Anti-hCD3 and Anti-Human MSLN scFv (CBL-YF049) 4-1BB-CD3ζ CAR, pCDCAR1 Human CBL-YF049 Humanized 7H-YB-NKG2DL Anti-hCD3 and (OKT3 scFv-NKG2D ECD)-EF1a-scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-YF471 TS-NKG2DL Anti-hCD3 and Anti-Human MSLN scFv (M5) 4-1BB-CD3ζ CAR, pCDCAR1 Human M5 Human 7H-YB-NKG2DL Anti-hCD3 and (OKT3 scFv-NKG2D ECD)-EF1a-scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-YF529 TS-NKG2DL Anti-hCD3 and Anti-Human MSLN scFv (m912) CD28-4-1BB-CD3ζ CAR, pCDCAR1 Human m912 Human 7H-YB-NKG2DL Anti-hCD3 and (OKT3 scFv-NKG2D ECD)-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-YF530 TS-NKG2DL Anti-hCD3 and Anti-Human MSLN scFv (CBL-YF049) CD28-4-1BB-CD3ζ CAR, pCDCAR1 Human CBL-YF049 Humanized 7H-YB-NKG2DL Anti-hCD3 and (OKT3 scFv-NKG2D ECD)-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-YF531 TS-NKG2DL Anti-hCD3 and Anti-Human MSLN scFv (M5) CD28-4-1BB-CD3ζ CAR, pCDCAR1 Human M5 Human 7H-YB-NKG2DL Anti-hCD3 and (OKT3 scFv-NKG2D ECD)-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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