Creative Biolabs has a tradition of commitment. To achieve efficient execution and regulatory approval, we offer careful considerations of your program for the development of a cellular or gene therapy product – now and in the future.
EXPLORE MORE HighlightsWe focus on unmet needs and develop novel cellular and gene drugs and solutions that offer significant benefits over existing options.
EXPLORE MORE HighlightsThe advent of Chimeric Antigen Receptor T-cell (CAR-T) therapies has revolutionized the field of oncology, providing new avenues for treating various forms of cancer. Our 20 years of experience in the biotechnology sector have equipped us with the expertise and technological capabilities to support the entire lifecycle of CAR-T products, from early development to commercialization.
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EXPLORE MORE HighlightsUse the resources in our library to help you understand your options and make critical decisions for your study. We offer oncolytic virus, CAR-T, and dendritic cell related documents, as well as newsletter. If you don't find the answers you're looking for, contact us for additional assistance.
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Tyrosine-protein kinase transmembrane receptor ROR1, also called neurotrophic tyrosine kinase receptor-related 1 (NTRKR1), belongs to the receptor tyrosine kinase-like orphan receptor (ROR) subfamily. It is a type I membrane protein, which is regulating neurite growth in the central nervous system. ROR1 is playing a functional role in the activity of ovarian cancer cells, and associated with B-cell chronic lymphocytic leukaemia.
Associated Disease
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| CAT | Product Name | Target Species | Antibody Clone | Antibody Host | Receptor Construction | Vector Type | Targeting Cell Type | CAR Vector Type | Inquiry & Datasheet |
| CAR-T-1-M324-2 | Anti-ROR1 scFv h(CD28) CART, pCDCAR1 | Human | 2A2 | Mouse | scFv-CD28 | Lentiviral | T cell | ||
| CAR-T-1-M324-G | Anti-ROR1 scFv h(FcεRIγ) CART, pCDCAR1 | Human | 2A2 | Mouse | scFv-FcεRIγ | Lentiviral | T cell | ||
| CAR-T-1-M324-Z | Anti-ROR1 scFv h(CD3ζ) CART, pCDCAR1 | Human | 2A2 | Mouse | scFv-CD3ζ | Lentiviral | T cell | ||
| CAR-T-2-M324-2G | Anti-ROR1 scFv h(CD28-FcεRIγ) CART, pCDCAR1 | Human | 2A2 | Mouse | scFv-CD28-FcεRIγ | Lentiviral | T cell | ||
| CAR-T-2-M324-2Z | Anti-ROR1 scFv h(CD28-CD3ζ) CART, pCDCAR1 | Human | 2A2 | Mouse | scFv-CD28-CD3ζ | Lentiviral | T cell | ||
| CAR-YF106 | Anti-ROR1 (CBL-YF035) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | CBL-YF035 | Human | scFv-4-1BB-CD3ζ | Lentiviral vector | T cell | ||
| CAR-YF107 | Anti-ROR1 (CBL-YF035) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | CBL-YF035 | Human | scFv-CD28-CD3ζ | Lentiviral vector | T cell | ||
| CAR-YF112 | Anti-ROR1 (R11) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | R11 | Rabbit | scFv-4-1BB-CD3ζ | Lentiviral vector | T cell | ||
| CAR-YF113 | Anti-ROR1 (R11) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | R11 | Rabbit | scFv-CD28-CD3ζ | Lentiviral vector | T cell | ||
| CAR-ZP091 | Anti-RoR1 (R11) h(41BB-CD3ζ) CAR, pCDCAR1 | Human | R11 | Rabbit | scFv-4-1BB-CD3ζ | Lentiviral vector | T cell | ||
| CAR-SB-LX0411 | Anti-ROR1 (601-3-16) h(CD28-CD3ζ) CAR, pSBCAR1 | Human | 601-3-16 | Human | scFv-CD28-CD3ζ | Sleeping Beauty (SB) transposon | T cell | ||
| CAR-SB-LX0412 | Anti-ROR1 (601-3-12) h(CD28-CD3ζ) CAR, pSBCAR1 | Human | 601-3-12 | Human | scFv-CD28-CD3ζ | Sleeping Beauty (SB) transposon | T cell | ||
| CAR-SB-LX0413 | Anti-ROR1 (V70) h(CD28-CD3ζ) CAR, pSBCAR1 | Human | V70 | Human | scFv-CD28-CD3ζ | Sleeping Beauty (SB) transposon | T cell | ||
| CAR-SB-LX0414 | Anti-ROR1 (EML719) h(CD28-CD3ζ) CAR, pSBCAR1 | Human | EML719 | Human | scFv-CD28-CD3ζ | Sleeping Beauty (SB) transposon | T cell | ||
| CAR-SB-LX0415 | Anti-ROR1 (31C12) h(CD28-CD3ζ) CAR, pSBCAR1 | Human | 31C12 | Mouse | scFv-CD28-CD3ζ | Sleeping Beauty (SB) transposon | T cell | ||
| XS-0823-LX87 | Anti-hROR1 (12) ICD(CD28-OX40-CD3ζ) CAR-MA, pAd5f35 Vector | Human | 12 | Adenoviral vectors |
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NEW SOLUTION
CellRapeutics™ In Vivo Cell Engineering: One-stop in vivo T/B/NK cell and macrophage engineering services covering vectors construction to function verification.
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Silence™ CAR-T Cell: A novel platform to enhance CAR-T cell immunotherapy by combining RNAi technology to suppress genes that may impede CAR functionality.
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Canine CAR-T Therapy Development: From early target discovery, CAR design and construction, cell culture, and transfection, to in vitro and in vivo function validation.
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