Complement C1 Peptide Inhibitor-PIC1 is a highly potent C1 inhibitor which can inhibit ~90% complement activity in a hemolytic assay at Conc. 0.77mM. This inhibitor specifically inhibits the classical and lectin pathways of complement by binding to C1q, it also can bound to the lectin pathway initiator molecule MBL as well as the ficolins H, M and L.
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Purity | 0.95 |
Solubility | Soluble in water |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Target | C1q |
Introduction | The complement component 1q (C1q) is a protein complex involved in the complement system, which is also a subunit of the first complement component C1. When C1q binds antigen-antibody complexes, the C1 complex becomes activated. Activation of the C1 complex initiates the classical complement pathway of the complement system. |
Become a staple in our labExcellentUsed this inhibitor in my lab for complement cascade studies. Impressed by its efficacy and consistency. As a researcher, finding reliable inhibitors is crucial. PIC1 exceeded my expectations. Great results every time.
This inhibitor is top-notchExcellentI've tried several inhibitors in the past, but PIC1 stands out for its reliability and performance. PIC1 has become our go-to inhibitor for studying complement pathways. It's highly effective and easy to work with. Definitely recommend it.
Easy to handle and very effectiveExcellentI bought complement C1 peptide inhibitor-PIC1 for use in my laboratory three months ago. So far, it has enhanced the quality of my data several folds. I am impressed by how stable this product is!
Five stars, for sureExcellentComplement C1 peptide inhibitor-PIC1 is pure and stable. Our data has been highly consistent with this product. My team and I are extremely pleased with PIC1. We will surely be repurchasing it.