This product is an Anti-Human C1 Inhibitor Polyclonal Antiserum from goats immunized with highly purified human C1 Inhibitor protein. It is not a purified IgG fraction.
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Host Animal | Goats |
Isotype | IgG |
Immunogen | C1 Inhibitor protein |
Applications | Western Blots; ELISA; Immunodiffusion |
Application Notes | Immunodiffusion: 1/4; WB: 1/500 to 1/2000; ELISA: 1/500 to 1/4000 |
Specificity | C1 Inhibitor |
Format | Frozen liquid |
Size | 1ml |
Storage | Store at 4°C short term. Store at -20°C or below long term. Avoid freeze-thaw cycles. |
Target Name | C1 Inhibitor |
Alternative Names | Serpin Family G Member 1; Plasma Protease C1 Inhibitor; C1IN; Serpin Peptidase Inhibitor, Clade G (C1 Inhibitor), Member 1; C1 Esterase Inhibitor; C1-Inhibiting Factor;C1-Inhibitor; C1INH; ; Serine/Cysteine Proteinase Inhibitor Clade G Member 1; Epididymis Secretory Sperm Binding Protein; Complement Component 1 Inhibitor; SERPING1; C1-INH; C1Inh |
Gene ID | 710 |
UniProt ID | P05155 |
Introduction | Activation of the C1 complex is under control of the C1-inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein. |