This product is a 19.0 kDa recombinant rat Complement 1 Inhibitor with two N-terminal Tags (His-tag and S-tag) expressed in the E. Coli. It is available for WB, ELISA, IP.
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Expressed Host | E. Coli |
Specie Reactivity | Rat |
Target | C1 Inhibitor |
Molecule Mass | 19.0 kDa |
Purity | >95% as determined by SDS-PAGE |
Endotoxin | <1.0EU per 1µg (determined by the LAL method) |
Formulation | PBS, pH 7.4, containing 5% sucrose, 0.01% sarcosyl |
Applications | WB; ELISA; IP |
Product Form | Lyophilized |
Storage | Store at 2 to 8°C after reconstitution for short term (1-2 weeks). For long term storage, aliquot and store at -20 or -80°C. Avoid repeated freezing and thawing cycles. |
Introduction | Activation of the C1 complex is under control of the C1-inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein. |
Alternative Names | Plasma protease C1 inhibitor; C1-IA; C1 Inh; C1 esterase inhibitor; C1-inhibiting factor; Serpin G1 |
Gene ID | 295703 |
UniProt ID | Q6P734 |