This product is an ELISA kit for the determination of Human Complement Factor D in the samples of Plasma and Serum. It is highly sensitive and available for the detection of Human Complement Factor D as low as 0.238 ng/mL.
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Assay Type | CLIA (chemiluminescent immunoassay) |
Sensitivity | 0.238 ng/mL (0.625-40 ng/mL) |
Pack Size | 96 tests |
Species Reactivity | Human |
Target | Factor D |
Cross Reactivity | No significant cross-reactions have been observed between Human Complement Factor D and analogues, but existing techniques may limit the detection of cross-reactions with untested analogues. |
Applications | ELISA |
Storage | The storage of components varies. Please refer to the instructions for details. |
Introduction | Complement factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. It also involves in selective cleavage of Arg-|-Lys bond in complement factor B when in complex with complement subcomponent C3b or with cobra venom factor. |