Mouse Anti-Human Complement C4BPA Monoclonal Antibody (CTJS-873)(Cat#: CTA-244)
This product is an unconjugated anti-Human Complement C4BPA Monoclonal antibody (CTJS-873) generated from the Mouse. The antibody can be used for ELISA; IHC.
Summary
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Specifications
| Clonality |
Monoclonal |
| Clone |
CTJS-873 |
| Host Animal |
Mouse |
| Isotype |
IgG2b |
| Immunogen |
Native human C4 binding protein |
| Species Reactivity |
Human |
| Applications |
ELISA; IHC |
| Application Notes |
ELISA: 1:100 - 1:2000
IHC: 5 µg/mL
The optimal working dilutions should be determined by the end user. |
| Specificity |
This antibody reacts with Human complement C4BPA. |
| Purity |
≥95% as determined by SDS-PAGE |
| Format |
Liquid |
| Size |
50 µg |
| Storage |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
| Type |
Primary Antibody |
Target
| Target Name |
C4bPA |
| Alternative Names |
C4b binding protein alpha chain; C4b-binding protein alpha chain; C4BP; complement component 4 binding protein alpha chain; complement component 4 binding protein alpha; complement component 4-binding protein alpha; Proline-rich protein; PRP |
| Gene ID |
722 |
| UniProt ID |
P04003 |
Information
| Introduction |
C4b-binding protein alpha chain is encoded by the human C4BPA gene. It controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. It interacts also with anticoagulant protein S and with serum amyloid P component. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
