This product is an unconjugated anti-Human Complement Factor I Monoclonal antibody (CTJS-518) generated from the Mouse. The antibody can be used for WB; IHC.
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Clonality | Monoclonal |
Clone | CTJS-518 |
Host Animal | Mouse |
Isotype | IgG2a |
Immunogen | Recombinant protein fragment corresponding to amino acids 340-583 of human Complement Factor I produced in E.coli. |
Species Reactivity | Human |
Applications | WB; IHC |
Application Notes | WB: 1:2000 IHC: 1:150 The optimal working dilutions should be determined by the end user. |
Specificity | This antibody reacts with Human complement Factor I. |
Purity | ≥95% as determined by SDS-PAGE |
Format | Liquid |
Size | 100 µL |
Storage | Store at -20°C. Avoid freeze-thaw cycles. |
Type | Primary Antibody |
Target Name | Factor I |
Alternative Names | Konglutinogen-Activating Factor; C3B/C4B Inactivator; C3b-Inactivator; Complement Control Protein Factor I; Complement Factor I Heavy Chain; Light Chain Of Factor I; Complement Component I; I Factor (Complement); EC 3.4.21.45; FI; IF; KAF; AHUS3; ARMD13; C3BINA; C3b-INA |
Gene ID | 3426 |
UniProt ID | P05156 |
Introduction | Complement factor I, also known as C3b/C4b inactivator, is a protein that in humans is encoded by the CFI gene. Complement factor I (factor I) is a protein of the complement system, first isolated in 1966 in guinea pig serum, that regulates complement activation by cleaving cell-bound or fluid phase C3b and C4b. It is a soluble glycoprotein that circulates in human blood at an average concentration of 35 μg/mL. |