Mouse Anti-Human Vitronectin Monoclonal Antibody (CTJS-742)(Cat#: CTA-186)
This product is an unconjugated anti-Human Vitronectin Monoclonal antibody (CTJS-742) generated from the Mouse. The antibody can be used for WB; ELISA; FC; IHC.
Summary
Related Products & Services
Specifications
| Clonality |
Monoclonal |
| Clone |
CTJS-742 |
| Host Animal |
Mouse |
| Isotype |
IgG2b |
| Immunogen |
Purified recombinant fragment of human VTN (AA: 20-199) expressed in E. Coli. |
| Species Reactivity |
Human |
| Applications |
WB; ELISA; FC; IHC |
| Application Notes |
WB: 1:500-1:2000
ELISA: 1:10000
FC: 1:200-1:400
IHC: 1:200-1:1000
The optimal working dilutions should be determined by the end user. |
| Specificity |
This antibody reacts with Human Vitronectin. |
| Purity |
≥95% as determined by SDS-PAGE |
| Format |
Liquid |
| Size |
25; 100 µg |
| Storage |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
| Type |
Primary Antibody |
Target
| Target Name |
Vitronectin |
| Alternative Names |
Serum Spreading Factor; Complement S-Protein; Somatomedin B; S-Protein; V75; VN; Vitronectin (Serum Spreading Factor, Somatomedin B, Complement S-Protein); Serum-Spreading Factor; Epibolin; VNT |
| Gene ID |
7448 |
| UniProt ID |
P04004 |
Information
| Introduction |
Vitronectin (VTN or VN) is a glycoprotein of the hemopexin family which is abundantly found in serum, the extracellular matrix and bone.In humans it is encoded by the VTN gene. Vitronectin binds to integrin alpha-V beta-3 and thus promotes cell adhesion and spreading. It also inhibits the membrane-damaging effect of the terminal cytolytic complement pathway and binds to several serpins (serine protease inhibitors). It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond. Vitronectin has been speculated to be involved in hemostasis and tumor malignancy. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
