This product is a 52.3 kDa recombinant human Vitronectin protein expressed in the mouse myeloma cell line, NS0. It is available for Bioactivity Assays.
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Expressed Host | Mouse myeloma cell line, NS0 |
Specie Reactivity | Human |
Target | Vitronectin |
Molecule Mass | 52.3 kDa |
Purity | >90% by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie Blue Staining |
Endotoxin | <1.0EU per 1µg (determined by the LAL method) |
Formulation | Tris and NaCl |
Applications | Bioactivity Assays |
Product Form | Lyophilized |
Storage | Store at 2 to 8°C after reconstitution for short term (1-2 weeks). For long term storage, aliquot and store at -20 or -80°C. Avoid repeated freezing and thawing cycles. |
Introduction | Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway. Somatomedin-B is a growth hormone-dependent serum factor with protease-inhibiting activity. |
Alternative Names | Complement S-protein; epibolin; Serum Spreading Factor; Serum-spreading factor; Somatomedin B; S-protein; V75; vitronectin (serum spreading factor, somatomedin B, complement S-protein); Vitronectin; VN; VNT; VTN |
Gene ID | 7448 |
UniProt ID | P04004 |