Mouse Anti-Porcine Complement C5a/C5a des Arg Monoclonal Antibody (CTJS-396)(Cat#: CTA-530)

Name: Mouse Anti-Porcine Complement C5a/C5a des Arg Monoclonal Antibody (CTJS-396)
SKU: CTA-530
Rating: 5 (1 reviews)

This product is an anti-Porcine Complement C5a/C5a des Arg Monoclonal antibody (CTJS-396) generated from the Mouse. The antibody can be used for WB; ELISA; IP; FuncS.

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Specifications

Clonality	Monoclonal
Clone	CTJS-396
Host Animal	Mouse
Isotype	IgG1, κ
Immunogen	Purified porcine C5a
Species Reactivity	Porcine
Applications	WB; ELISA; IP; FuncS
Application Notes	The optimal working dilutions should be determined by the end user.
Specificity	This antibody reacts with Porcine complement C5a/C5a des Arg.
Purity	≥95% as determined by SDS-PAGE
Format	Liquid
Size	100ug
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Type	Primary Antibody

Target

Target Name	C5a
Alternative Names	Complement C5a; C5a des-Arg; Inactivated C5a
Gene ID	727
UniProt ID	P01031

Information

Introduction

Complement C5a, together with C5b, are protein fragments released from cleavage of complement component C5 by protease C5-convertase. C5a is a chemotactic agent, as well as an anaphylatoxin, playing critical roles in migration and adherence of neutrophils and monocytes, smooth muscle contraction, and vascular permeability increase. Once complement C5a is produced, it rapidly metabolised inti C5a desArg by a serum enzyme carboxypeptidase B through removal of the C terminal arginine. Compared with C5a, C5a des-Arg is a much less potent anaphylatoxin that alsi induces C5a biological activities.

For Research Use Only. Not for Diagnostic or Therapeutic Applications.