This product is a 10.4 kDa native human C5a protein isolated from normal human serum. It is availible for Functional Assays, ELISA, RIA.
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Specie Reactivity | Human |
Target | C5a |
Molecule Mass | 10.4 kDa |
Purity | >97% determined by SDS-PAGE |
Endotoxin | <1.0EU per 1µg (determined by the LAL method) |
Formulation | 20 mM HEPES, 100 mM NaCl, pH 7.2 |
Applications | Functional Assays; ELISA; RIA |
Product Form | Frozen liquid |
Storage | Store at -20°C/-80°C. Avoid freeze-thaw cycles. |
Introduction | Complement C5a, together with C5b, are protein fragments released from cleavage of complement component C5 by protease C5-convertase. C5a is a chemotactic agent, as well as an anaphylatoxin, playing critical roles in migration and adherence of neutrophils and monocytes, smooth muscle contraction, and vascular permeability increase. |
Alternative Names | Complement C5a; C5a fragment; C5a anaphylatoxin |
Gene ID | 727 |
UniProt ID | P01031 |
A crucial component in my researchExcellentThe protein's high purity and consistent activity have made it a reliable reagent for my assays. I particularly appreciate the detailed datasheet provided, which includes critical information on concentration and stability. This product has consistently delivered accurate results in our experiments.
A standout productExcellentThe protein's activity was maintained throughout its use, and the quality was top-notch. The customer service team was also very helpful in answering technical questions regarding its application in our experimental setup. Overall, a highly satisfactory experience.
Exceptional for our ELISA assaysExcellentIts high purity and stability have significantly improved the reproducibility of our results. We appreciate the detailed product documentation and the excellent customer support from the supplier. This protein has become a critical component of our research into complement system activation.
We've been using this C5a protein for several months nowExcellentThe quality is top-notch, with consistent activity across multiple experiments. It has helped us to better understand the inflammatory pathways we are studying. Highly recommended for anyone needing reliable complement components.
For our RIA studiesExcellentWe were impressed by its purity and the absence of cross-reactivity with other proteins. The batch-to-batch consistency has ensured reliable data for our ongoing projects. The customer service team was also very helpful with our queries.