Rabbit Anti-Human Vitronectin Polyclonal Antiserum(Cat#: CTA-P-022)
This product is an Anti-Human Vitronectin Polyclonal Antiserum from rabbits immunized with highly purified human Vitronectin protein. It is not a purified IgG fraction.
Summary
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Specifications
| Host Animal |
Rabbits |
| Isotype |
IgG |
| Immunogen |
Vitronectin protein |
| Applications |
Western Blots; ELISA; Immunodiffusion |
| Application Notes |
Immunodiffusion: 1/8;
WB: 1/500 to 1/1000;
ELISA: 1/500 to 1/2000 |
| Specificity |
Vitronectin |
| Format |
Frozen liquid |
| Size |
1ml |
| Storage |
Store at 4°C short term. Store at -20°C or below long term. Avoid freeze-thaw cycles. |
Target
| Target Name |
Vitronectin |
| Alternative Names |
Serum Spreading Factor; Complement S-Protein; Somatomedin B; S-Protein; V75; VN; Vitronectin (Serum Spreading Factor, Somatomedin B, Complement S-Protein); Serum-Spreading Factor; Epibolin; VNT |
| Gene ID |
7448 |
| UniProt ID |
P04004 |
Information
| Introduction |
Vitronectin (VTN or VN) is a glycoprotein of the hemopexin family which is abundantly found in serum, the extracellular matrix and bone.In humans it is encoded by the VTN gene. Vitronectin binds to integrin alpha-V beta-3 and thus promotes cell adhesion and spreading. It also inhibits the membrane-damaging effect of the terminal cytolytic complement pathway and binds to several serpins (serine protease inhibitors). It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond. Vitronectin has been speculated to be involved in hemostasis and tumor malignancy. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
