This product is an ELISA kit for the determination of Rat Complement C4bpa in the samples of Serum, Plasma, Tissue Homogenate. It is highly sensitive and available for the detection of Rat Complement C4bpa as low as 39 ng/mL.
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Assay Type | Sandwich ELISA |
Sensitivity | 39 ng/mL (78-5000 ng/mL) |
Pack Size | 96 tests |
Species Reactivity | Rat |
Target | C4BPA |
Cross Reactivity | No significant cross-reactions have been observed between Rat Complement C4bpa and analogues, but existing techniques may limit the detection of cross-reactions with untested analogues. |
Applications | ELISA |
Storage | Short-term storage at 4°C and long-term storage at -20°C. |
Introduction | C4b-binding protein alpha chain controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. It interacts also with anticoagulant protein S and with serum amyloid P component. |