This product is a recombinant human C4BPA protein with a N-terminal His Tag tag expressed in the E.coli. It is availible for WB, ELISA, IP.
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Expressed Host | E.coli |
Specie Reactivity | Human |
Target | C4BPA |
Purity | >95 % determined by SDS-PAGE |
Endotoxin | <1.0EU per 1µg (determined by the LAL method) |
Formulation | 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300 |
Applications | WB; ELISA; IP |
Product Form | Lyophilized |
Storage | Store at -20°C/-80°C. Avoid freeze-thaw cycles. |
Introduction | Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. It interacts also with anticoagulant protein S and with serum amyloid P component. |
Alternative Names | Complement Component 4 Binding Protein Alpha; C4b-Binding Protein Alpha Chain ; Proline-Rich Protein; C4BP; Complement Component 4-Binding Protein, Alpha; C4BPA; C4bp |
Gene ID | 722 |
UniProt ID | P04003 |