This product is an ELISA kit for the determination of Rat Complement Factor D in the samples of Plasma, Serum and Tissue Homogenates. It is highly sensitive and available for the detection of Rat Complement Factor D as low as 0.134 ng/mL.
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Assay Type | Sandwich ELISA |
Sensitivity | 0.134 ng/mL (0.312-20 ng/mL) |
Pack Size | 96 tests |
Species Reactivity | Rat |
Target | Factor D |
Cross Reactivity | No significant cross-reactions have been observed between Rat Complement Factor D and analogues, but existing techniques may limit the detection of cross-reactions with untested analogues. |
Applications | ELISA |
Storage | Short-term storage at 4°C and long-term storage at -20°C. |
Introduction | Complement factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. It also involves in selective cleavage of Arg-|-Lys bond in complement factor B when in complex with complement subcomponent C3b or with cobra venom factor. |