This product is a 25.8 kDa recombinant human C1QA protein with a N-terminal His tag expressed in the E. Coli. It is available for WB, ELISA, PA.
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Expressed Host | E. Coli |
Specie Reactivity | Human |
Target | C1QA |
Molecule Mass | 25.8 kDa |
Purity | >80% as determined by SDS-PAGE and Coomassie Blue staining |
Formulation | 50mM Tris, 8M Urea, pH 8.0 |
Applications | WB; ELISA; PA |
Product Form | Liquid |
Storage | Store at -20/-80°C. Aliquot to avoid repeated freezing and thawing. |
Introduction | Complement C1q subcomponent subunit A is a protein that in humans is encoded by the C1QA gene. C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca2+-dependent C1r2C1s2 proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. |
Alternative Names | Complement C1q A Chain; Complement Component 1, Q Subcomponent, Alpha Polypeptide; Complement Component 1, Q Subcomponent, A Chain; Complement C1q Chain A; Complement C1q Subcomponent Subunit A; Complement Component C1q, A Chain |
Gene ID | 712 |
UniProt ID | P02745 |