This product is a 86.13 kDa recombinant human C4BPA protein with a GST-tag at N-terminal expressed in the Wheat Germ (in vitro). It is available for WB, ELISA, PA, AP.
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Expressed Host | Wheat Germ (in vitro) |
Specie Reactivity | Human |
Target | C4BPA |
Molecule Mass | 86.13 kDa |
Purity | >80% by SDS-PAGE and Coomassie Blue staining |
Formulation | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH 8.0 |
Applications | WB; ELISA; PA; AP |
Product Form | Liquid |
Storage | Store at -20/-80°C. Aliquot to avoid repeated freezing and thawing. |
Introduction | C4b-binding protein alpha chain controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. It interacts also with anticoagulant protein S and with serum amyloid P component. |
Alternative Names | C4b binding protein alpha chain; C4b-binding protein alpha chain; C4BP; complement component 4 binding protein alpha chain; complement component 4 binding protein alpha; complement component 4-binding protein alpha; Proline-rich protein; PRP |
Gene ID | 722 |
UniProt ID | P04003 |