shRNA Adenovirus Serotype 5 (ΔE1/E3), p7SK-(TMEM205-shRNA-Seq1)(CAT#: AdV-SI1342WQ)
This product is a TMEM205-shRNA encoding AdV, which is based on AdV-5 serotype with EIB-55K gene deleted. Elevated expression of TMEM205, a hypothetical membrane protein, is associated with cisplatin resistance. The expression of TMEM205-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
Specifications | |
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Family | Adenoviridae |
Species | Adenovirus |
Serotype | HAdV-5 |
Backbone | AdV-5 (ΔE1/E3) |
Tropism | Both nondividing and dividing cells |
Insert | TMEM205-shRNA-Seq1 |
Related Target/Protein | TMEM205 |
Region | CDS |
TargetSeq | CTGATTAAGATGGTCCATCTA |
NCBI RefSeq | NM_198536 |
Alternative Names | UNQ501 |
Titer | >1*10^10 GC/mL |
Related Diseases | Ovarian cancer |