shRNA Lentivirus (self-inactivating), pU6-(C12orf48-shRNA-Seq1)(CAT#: LV-SI0272WQ)
This product is a C12orf48-shRNA encoding Lentivirus, which is based on HIV-1 serotype. The C12orf48 is required to suppress inappropriate homologous recombination, thereby playing a central role DNA repair and in the maintenance of genomic stability. The expression of C12orf48-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
| Specifications | |
|---|---|
| Family | Retroviridae |
| Species | Lentivirus |
| Serotype | HIV-1 |
| Backbone | Lenti-SIN |
| Tropism | Both nondividing and dividing cells |
| Insert | C12orf48-shRNA-Seq1 |
| Related Target/Protein | C12orf48 |
| Region | CDS |
| TargetSeq | CAAACTAGCTAAAGTAGCAAA |
| NCBI RefSeq | NM_017915 |
| Alternative Names | AROM; PARI; PARPBP |
| Titer | >1*10^10 GC/mL |
| Related Diseases | Hepatocellular Carcinoma |
