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Magic™ Antibody Discovery - Human Cystatin S / CST4 (21-141) Membrane Protein, Partial, -His tag (CAT#: MP1183F)

Datasheet
This membrane protein is Human Cystatin S / CST4 (21-141). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • Cystatin S / CST4
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 15.0 kDa. The protein migrates as 15 kDa under reducing (R) condition (SDS-PAGE).
  • Sequence
  • AA Ser 21 - Ala 141 (Accession # AAH65714).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • HEK293
  • Tag
  • His tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in 25 mM MES, 150 mM NaCl, pH6.0. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • Cystatin S / CST4
  • Full Name
  • cystatin S
  • Introduction
  • The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a type 2 salivary cysteine peptidase inhibitor. The protein is an S-type cystatin, based on its high level of expression in saliva, tears and seminal plasma. The specific role in these fluids is unclear but antibacterial and antiviral activity is present, consistent with a protective function.
  • Alternative Names
  • CST4, cystatin S, cystatin-S, cystatin 4, cystatin-4, cystatin-SA-III, salivary acidic protein 1, MGC71923,

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