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Magic™ Antibody Discovery - Human VEGF165 (27-191) Membrane Protein, Partial, His- Avi- tag, [Biotin] (CAT#: MP0533F)

Datasheet
This membrane protein is Human VEGF165 (27-191). It has been tested in SDS-PAGE, ELISA, SPR. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • VEGF165
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 22.4 kDa (monomer). As a result of glycosylation, the protein migrates as 25-33 kDa (monomer) under reducing (R) condition, and 42-55 kDa (homodimer) under non-reducing (NR) condition (SDS-PAGE).
  • Sequence
  • AA Ala 27 - Arg 191 (Accession # P15692-4).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, ELISA, SPR
  • Expression Systems
  • HEK293
  • Tag
  • His tag at the N-terminus, followed by an Avi tag
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Conjugation
  • Biotin
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • VEGF165
  • Full Name
  • neuropilin 1
  • Introduction
  • This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. This protein has also been determined to act as a co-receptor for SARS-CoV-2 (which causes COVID-19) to infect host cells.
  • Alternative Names
  • NP1; NRP; BDCA4; CD304; VEGF165R; neuropilin-1; transmembrane receptor; vascular endothelial cell growth factor 165 receptor

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