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Magic™ Antibody Discovery - Mouse CD73 (29-551) Membrane Protein, Partial, -His tag (CAT#: MP1312F)

Datasheet
This membrane protein is Mouse CD73 (29-551). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Mouse
  • Target Protein
  • CD73
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 59.9 kDa. The protein migrates as 66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Trp 29 - Ser 551 (Accession # Q61503-1).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • HEK293
  • Tag
  • His tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >90% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in 20 mM Tris, 120 mM NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • CD73
  • Full Name
  • 5' nucleotidase, ecto
  • Introduction
  • This gene encodes a membrane-bound nucleotidase that hydrolyzes extracellular nucleoside monophosphates. The encoded preproprotein undergoes proteolytic processing to generate to a functional, homodimeric enzyme that preferentially uses adenosine monophosphate as a substrate to generate free adenosine. Mice lacking the encoded protein exhibit a significantly reduced fall in stop flow pressure and superficial nephron glomerular filtration rate in response to a saturating increase of tubular perfusion flow.
  • Alternative Names
  • NT; Nt5; eNT; CD73; 5'-NT; AI447961; 2210401F01Rik; 5'-nucleotidase; ecto-5'-nucleotidase

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