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Magic™ Human ABCC3 Membrane Protein Expressed in E. coli, Partial (1291-1523 aa) (CAT#: S01YF-0824-KX2)

Datasheet
This product is recombinant Human ABCC3 protein.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ABCC3
  • Protein Length
  • ECD
  • Protein Class
  • Transporter
  • Molecular Weight
  • 29.5 kDa
  • TMD
  • 17
  • Sequence
  • Phe 1291 - Asp 1523

Product Description

  • Expression Systems
  • E. coli expression system
  • Tag
  • His tag at the N-terminus
  • Protein Format
  • Soluble
  • Buffer
  • PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.

Target

  • Target Protein
  • ABCC3
  • Full Name
  • ATP binding cassette subfamily C member 3
  • Introduction
  • The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
  • Alternative Names
  • MLP2; MRP3; ABC31; MOAT-D; cMOAT2; EST90757; ATP-binding cassette sub-family C member 3; ATP-binding cassette, sub-family C (CFTR/MRP), member 3; canalicular multispecific organic anion transporter 2; canicular multispecific organic anion transporter; multi-specific organic anion transporter D; multidrug resistance associated protein; multidrug resistance-associated protein 3; ABCC3; ATP binding cassette subfamily C member 3
  • Gene ID
  • 8714
  • UniProt ID
  • O15438

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