Close
Close

Magic™ Human MMP-14 Membrane Protein Expressed in NS0, Partial (21-538 aa) (CAT#: S01YF-0824-KX7)

Datasheet
This product is recombinant Human MMP14 protein.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • MMP14
  • Protein Length
  • ECD
  • Protein Class
  • Protease
  • Molecular Weight
  • 60 kDa
  • TMD
  • 1
  • Sequence
  • Ala 21 - Ser 538 (Accession # P50281, with an Arg108Pro mutation)

Product Description

  • Expression Systems
  • NS0 expression system
  • Tag
  • 6xHis tag at the C-terminus
  • Protein Format
  • Soluble
  • Endotoxin
  • <1.0 EU per 1 μg of the protein by the LAL method.
  • Buffer
  • Supplied as a 0.2 μm filtered solution in Sodium Acetate, NaCl, CaCl2, Glycerol.

Target

  • Target Protein
  • MMP14
  • Full Name
  • Matrix metallopeptidase 14
  • Introduction
  • Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.
  • Alternative Names
  • MMP14; MMP-14; MMP-X1; MT-MMP; MT1MMP; MTMMP1; WNCHRS; MT1-MMP; MT-MMP 1; matrix metalloproteinase-14; matrix metallopeptidase 14 (membrane-inserted); membrane type 1 metalloprotease; membrane-type-1 matrix metalloproteinase; Matrix metallopeptidase 14
  • Gene ID
  • 4323
  • UniProt ID
  • P50281

Customer reviews and Q&As    

Related Products
Online Inquiry
CONTACT US
USA:
Europe:
Germany:
Call us at:
USA:
UK:
Germany:
Fax:
Email: info@creative-biolabs.com
Our customer service representatives are available 24 hours a day, 7 days a week. Contact Us
© 2025 Creative Biolabs. | Contact Us