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Magic™ Human SLC1A2 Membrane Protein in Detergent, Full Length (CAT#: S01YF-0723-KX164)

Datasheet
This product is Human SLC1A2 in detergent form.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SLC1A2
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • Molecular Weight
  • 66.0 kDa
  • TMD
  • 8
  • Sequence
  • AA 2-574 (Accession # P43004)

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; Antibody Production; Antibody Discovery; Antibody Characterization; Binding Assays; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the N-terminus and His tag at the C-terminus
  • Protein Format
  • Detergent
  • Endotoxin
  • <1.0 EU per μg by the LAL method.
  • Buffer
  • 50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5 with glycerol as protectant

Target

  • Target Protein
  • SLC1A2
  • Full Name
  • Solute carrier family 1 member 2
  • Introduction
  • This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Improper regulation of this gene is thought to be associated with several neurological disorders. Alternatively spliced transcript variants of this gene have been identified.
  • Alternative Names
  • HBGT; DEE41; EAAT2; GLT-1; EIEE41; excitatory amino acid transporter 2; excitotoxic amino acid transporter 2; glutamate/aspartate transporter II; sodium-dependent glutamate/aspartate transporter 2; solute carrier family 1 (glial high affinity glutamate transporter), member 2; SLC1A2; Solute carrier family 1 member 2

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