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Magic™ Membrane Protein Human ACVR1B (Activin A receptor type 1B) Full Length (CAT#: MPC1932K) Made to Order

This product is a 56.8 kDa Human ACVR1B membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ACVR1B
  • Protein Length
  • Full length
  • Protein Class
  • Transferase
  • Molecular Weight
  • 56.8 kDa
  • TMD
  • 1
  • Sequence
  • MAESAGASSFFPLVVLLLAGSGGSGPRGVQALLCACTSCLQANYTCETDG
    ACMVSIFNLDGMEHHVRTCIPKVELVPAGKPFYCLSSEDLRNTHCCYTDY
    CNRIDLRVPSGHLKEPEHPSMWGPVELVGIIAGPVFLLFLIIIIVFLVIN
    YHQRVYHNRQRLDMEDPSCEMCLSKDKTLQDLVYDLSTSGSGSGLPLFVQ
    RTVARTIVLQEIIGKGRFGEVWRGRWRGGDVAVKIFSSREERSWFREAEI
    YQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVT
    IEGMIKLALSAASGLAHLHMEIVGTQGKPGIAHRDLKSKNILVKKNGMCA
    IADLGLAVRHDAVTDTIDIAPNQRVGTKRYMAPEVLDETINMKHFDSFKC
    ADIYALGLVYWEIARRCNSGGVHEEYQLPYYDLVPSDPSIEEMRKVVCDQ
    KLRPNIPNWWQSYEALRVMGKMMRECWYANGAARLTALRIKKTLSQLSVQ
    EDVKI

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • ACVR1B
  • Full Name
  • Activin A receptor type 1B
  • Introduction
  • This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.
  • Alternative Names
  • ACVR1B; ALK4; SKR2; ACTRIB; ACVRLK4; activin receptor type-1B; activin A receptor, type IB; activin A receptor, type II-like kinase 4; activin receptor-like kinase 4; serine/threonine-protein kinase receptor R2; Activin A receptor type 1B
  • Gene ID
  • 91

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