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Magic™ Membrane Protein Human ADAM10 (ADAM metallopeptidase domain 10) Expressed in Baculovirus/Insect expression system for Antibody Discovery, Partial (214-672aa) (CAT#: MPX0109K)

Datasheet
This product is a 52 kDa Human ADAM10 membrane protein expressed in Baculovirus/Insect expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ADAM10
  • Protein Length
  • Partial (214-672aa)
  • Protein Class
  • Protease
  • Molecular Weight
  • 52 kDa
  • TMD
  • 1
  • Sequence
  • TTSAEKNTCQLYIQTDHLFFKYYGTREAVIAQISSHV
    KAIDTIYQTTDFSGIRNISFMVKRIRINTTADEKDPTNPFRFPNIGVEKF
    LELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLY
    SDGKKKSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHDSGTECT
    PGESKNLGQKENGNYIMYARATSGDKLNNNKFSLCSIRNISQVLEKKRNN
    CFVESGQPICGNGMVEQGEECDCGYSDQCKDECCFDANQPEGRKCKLKPG
    KQCSPSQGPCCTAQCAFKSKSEKCRDDSDCAREGICNGFTALCPASDPKP
    NFTDCNRHTQVCINGQCAGSICEKYGLEECTCASSDGKDDKELCHVCCMK
    KMDPSTCASTGSVQWSRHFSGRTITLQPGSPCNDFRGYCDVFMRCRLVDA
    DGPLARLKKAIFSPELYENIAE

Product Description

  • Expression Systems
  • Baculovirus/Insect expression system
  • Tag
  • 10xHis tag at the C-terminus
  • Protein Format
  • Soluble
  • Endotoxin
  • <0.01 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Buffer
  • Supplied as a 0.2 μm filtered solution in MES, NaCl, ZnCl2,Glycerol and Brij-35.

Target

  • Target Protein
  • ADAM10
  • Full Name
  • ADAM metallopeptidase domain 10
  • Introduction
  • Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. Alternate splicing results in multiple transcript variants encoding different proteins that may undergo similar processing.
  • Alternative Names
  • ADAM10; RAK; kuz; AD10; AD18; MADM; CD156c; CDw156; HsT18717; disintegrin and metalloproteinase domain-containing protein 10; a disintegrin and metalloprotease domain 10; kuzbanian protein homolog; mammalian disintegrin-metalloprotease; ADAM metallopeptidase domain 10

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