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Magic™ Membrane Protein Human PODXL (Podocalyxin like) Expressed in NS0 for Antibody Discovery, Partial (23-427aa) (CAT#: MPX0596K)

Datasheet
This product is a 43 kDa Human PODXL membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • PODXL
  • Protein Length
  • Partial (23-427aa)
  • Protein Class
  • Cell adhesion
  • Molecular Weight
  • 43 kDa
  • TMD
  • 1
  • Sequence
  • SPSPSPSPSPSQNATQTTTDSSNKTAPTPASSVTIMAT
    DTAQQSTVPTSKANEILASVKATTLGVSSDSPGTTTLAQQVSGPVNTTVARGGGSGNPTT
    TIESPKSTKSADTTTVATSTATAKPNTTSSQNGAEDTTNSGGKSSHSVTTDLTSTKAEHL
    TTPHPTSPLSPRQPTLTHPVATPTSSGHDHLMKISSSSSTVAIPGYTFTSPGMTTTLPSS
    VISQRTQQTSSQMPASSTAPSSQETVQPTSPATALRTPTLPETMSSSPTAASTTHRYPKT
    PSPTVAHESNWAKCEDLETQTQSEKQLVLNLTGNTLCAGGASDEKLISLICRAVKATFNP
    AQDKCGIRLASVPGSQTVVVKEITIHTKLPAKDVYERLKDKWDELKEAGVSDMKLGDQGP
    PEEAEDR

Product Description

  • Activity
  • Yes
  • Expression Systems
  • NS0
  • Tag
  • 10xHis tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 100 μg/mL in PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE with silver staining.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • PODXL
  • Full Name
  • Podocalyxin like
  • Introduction
  • This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.
  • Alternative Names
  • PODXL; PC; PDX; PCLP; Gp200; gp135; PCLP-1; PODXL1; podocalyxin; GCTM-2 antigen; podocalyxin-like protein 1; Podocalyxin like

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