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Magic™ Membrane Protein Human ATP1A2 (ATPase Na+/K+ transporting subunit alpha 2) Full Length (CAT#: MPC1156K) Made to Order

Datasheet
This product is a 112.2 kDa Human ATP1A2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ATP1A2
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • Molecular Weight
  • 112.2 kDa
  • TMD
  • 10
  • Sequence
  • MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELG
    RKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSI
    LLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEA
    KSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPAD
    LRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEG
    TARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFL
    GVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMA
    RKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADT
    TEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDTAGDAS
    ESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQSH
    VLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVL
    GFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAV
    GKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMS
    QVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVE
    GCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDD
    NFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLG
    TVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMA
    YGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYG
    QEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKI
    LIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDE
    VRKLILRRYPGGWVEKETYY

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • ATP1A2
  • Full Name
  • ATPase Na+/K+ transporting subunit alpha 2
  • Introduction
  • The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 2 subunit. Mutations in this gene result in familial basilar or hemiplegic migraines, and in a rare syndrome known as alternating hemiplegia of childhood.
  • Alternative Names
  • ATP1A2; FHM2; MHP2; sodium/potassium-transporting ATPase subunit alpha-2; ATPase Na+/K+ transporting alpha 2 polypeptide; Na(+)/K(+) ATPase alpha-2 subunit; Na+/K+ ATPase, alpha-A(+) catalytic polypeptide; Na+/K+ ATPase, alpha-B polypeptide; sodium pump subunit alpha-2; sodium-potassium ATPase catalytic subunit alpha-2; sodium/potassium-transporting ATPase alpha-2 chain; ATPase Na+/K+ transporting subunit alpha 2

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