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Magic™ Membrane Protein Human ATP1A4 (ATPase Na+/K+ transporting subunit alpha 4) Full Length (CAT#: MPC1158K) Made to Order

Datasheet
This product is a 114.1 kDa Human ATP1A4 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ATP1A4
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • Molecular Weight
  • 114.1 kDa
  • TMD
  • 10
  • Sequence
  • MGLWGKKGTVAPHDQSPRRRPKKGLIKKKMVKREKQKRNMEELKKEVVMD
    DHKLTLEELSTKYSVDLTKGHSHQRAKEILTRGGPNTVTPPPTTPEWVKF
    CKQLFGGFSLLLWTGAILCFVAYSIQIYFNEEPTKDNLYLSIVLSVVVIV
    TGCFSYYQEAKSSKIMESFKNMVPQQALVIRGGEKMQINVQEVVLGDLVE
    IKGGDRVPADLRLISAQGCKVDNSSLTGESEPQSRSPDFTHENPLETRNI
    CFFSTNCVEGTARGIVIATGDSTVMGRIASLTSGLAVGQTPIAAEIEHFI
    HLITVVAVFLGVTFFALSLLLGYGWLEAIIFLIGIIVANVPEGLLATVTV
    CLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMW
    FDMTVYEADTTEEQTGKTFTKSSDTWFMLARIAGLCNRADFKANQEILPI
    AKRATTGDASESALLKFIEQSYSSVAEMREKNPKVAEIPFNSTNKYQMSI
    HLREDSSQTHVLMMKGAPERILEFCSTFLLNGQEYSMNDEMKEAFQNAYL
    ELGGLGERVLGFCFLNLPSSFSKGFPFNTDEINFPMDNLCFVGLISMIDP
    PRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGTETAEEV
    AARLKIPISKVDASAAKAIVVHGAELKDIQSKQLDQILQNHPEIVFARTS
    PQQKLIIVEGCQRLGAVVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQ
    AADMILLDDNFASIVTGVEEGRLIFDNLKKSIMYTLTSNIPEITPFLMFI
    ILGIPLPLGTITILCIDLGTDMVPAISLAYESAESDIMKRLPRNPKTDNL
    VNHRLIGMAYGQIGMIQALAGFFTYFVILAENGFRPVDLLGIRLHWEDKY
    LNDLEDSYGQQWTYEQRKVVEFTCQTAFFVTIVVVQWADLIISKTRRNSL
    FQQGMRNKVLIFGILEETLLAAFLSYTPGMDVALRMYPLKITWWLCAIPY
    SILIFVYDEIRKLLIRQHPDGWVERETYY

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • ATP1A4
  • Full Name
  • ATPase Na+/K+ transporting subunit alpha 4
  • Introduction
  • The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 4 subunit. Alternatively spliced transcript variants encoding different isoforms have been identified.
  • Alternative Names
  • ATP1A4; ATP1A1; ATP1AL2; sodium/potassium-transporting ATPase subunit alpha-4; ATPase, Na+/K+ transporting, alpha 4 polypeptide; ATPase, Na+/K+ transporting, alpha polypeptide-like 2; Na(+)/K(+) ATPase alpha-4 subunit; Na+/K+ ATPase 4; Na+/K+ ATPase, alpha-D polypeptide; Na,K-ATPase subunit alpha-C; sodium pump 4; sodium pump subunit alpha-4; sodium-potassium ATPase catalytic subunit alpha-4; sodium/potassium-transporting ATPase alpha-4 chain; ATPase Na+/K+ transporting subunit alpha 4

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