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Magic™ Membrane Protein Human CCR6 (C-C motif chemokine receptor 6) expressed in E.coli for Antibody Discovery (CAT#: MP1335J)

Datasheet
This product is a 46.5 kDa Human CCR6 membrane protein expressed in E.coli. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CCR6
  • Protein Length
  • Full-length
  • Protein Class
  • GPCR
  • Molecular Weight
  • 46.5 kDa
  • TMD
  • 7
  • Sequence
  • MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISSSTFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKTLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQTSETADNDNASSFTM

Product Description

  • Expression Systems
  • E.coli
  • Tag
  • N-6xHis
  • Reconstitution
  • Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration).
  • Purity
  • >85% as determined by SDS-PAGE
  • Buffer
  • Liquid: Tris/PBS-based buffer, 5%-50% glycerol
    Lyophilized powder: Tris/PBS-based buffer, 6% Trehalose, pH 8.0

Target

  • Target Protein
  • CCR6
  • Full Name
  • C-C motif chemokine receptor 6
  • Introduction
  • This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene.
  • Alternative Names
  • BN 1; BN1; C C chemokine receptor type 6; C C CKR 6; C-C chemokine receptor type 6; C-C CKR-6; CC chemokine receptor type 6; CC CKR 6; CC R6; CC-CKR-6; CCCKR6; CCR 6; CCR-6; Ccr6; CCR6_HUMAN; CD 196; CD196; CD196 antigen; Chemokine (C C motif) receptor 6; Chemokine (C C) receptor 6; Chemokine (CC motif) receptor 6; Chemokine (CC) receptor 6; Chemokine receptor 6; Chemokine receptor like 3; Chemokine receptor-like 3; CKR 6; CKR L3; CKR-L3; CKR6; CKRL3; CMKBR 6; CMKBR6; DCR 2; DCR2; DRY 6; DRY6; G protein coupled receptor 29; G-protein coupled receptor 29; GPR 29; GPR CY4; GPR-CY4; GPR29; GPRCY 4; GPRCY4; LARC receptor; Seven transmembrane receptor lymphocyte 22; STRL 22; STRL22

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