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Magic™ Membrane Protein Human CDH18 (Cadherin 18) Full Length (CAT#: MPC2501K) Made to Order

This product is a made-to-order Human CDH18 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CDH18
  • Protein Length
  • Full length
  • Protein Class
  • Cell adhesion
  • TMD
  • 1
  • Sequence
  • MKITSTSCICPVLVCLCFVQRCYGTAHHSSIKVMRNQTKHIEGETEVHHR
    PKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAGTI
    FIIDDTTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQ
    DINDNAPKFTDGPYIVTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYS
    ILQGQPYFSVDPKTGVIRTALHNMDREAREHYSVVIQAKDMAGQVGGLSG
    STTVNITLTDVNDNPPRFPQKHYQLYVPESAQVGSAVGKIKANDADTGSN
    ADMTYSIINGDGMGIFSISTDKETREGILSLKKPLNYEKKKSYTLNIEGA
    NTHLDFRFSHLGPFKDATMLKIIVGDVDEPPLFSMPSYLMEVYENAKIGT
    VVGTVLAQDPDSTNSLVRYFINYNVEDDRFFNIDANTGTIRTTKVLDREE
    TPWYNITVTASEIDNPDLLSHVTVGIRVLDVNDNPPELAREYDIIVCENS
    KPGQVIHTISATDKDDFANGPRFNFFLDERLPVNPNFTLKDNEDNTASIL
    TRRRRFSRTVQDVYYLPIMISDGGIPSLSSSSTLTIRVCACERDGRVRTC
    HAEAFLSSAGLSTGALIAILLCVLILLAIVVLFITLRRSKKEPLIISEED
    VRENVVTYDDEGGGEEDTEAFDITALRNPSAAEELKYRRDIRPEVKLTPR
    HQTSSTLESIDVQEFIKQRLAEADLDPSVPPYDSLQTYAYEGQRSEAGSI
    SSLDSATTQSDQDYHYLGDWGPEFKKLAELYGEIESERTT

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • CDH18
  • Full Name
  • Cadherin 18
  • Introduction
  • This gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed specifically in the central nervous system and is putatively involved in synaptic adhesion, axon outgrowth and guidance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • CDH18; CDH14; CDH24; CDH14L; cadherin-18; cadherin 18, type 2; cadherin-14; cadherin-like 24; ey-cadherin; Cadherin 18

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