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Magic™ Membrane Protein Human CLSTN1 (Calsyntenin 1) Full Length (CAT#: MPC1359K) Made to Order

This product is a 109.7 kDa Human CLSTN1 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CLSTN1
  • Protein Length
  • Full length
  • Protein Class
  • Cell adhesion
  • Molecular Weight
  • 109.7 kDa
  • TMD
  • 1
  • Sequence
  • MLRRPAPALAPAARLLLAGLLCGGGVWAARVNKHKPWLEPTYHGIVTEND
    NTVLLDPPLIALDKDAPLRFAESFEVTVTKEGEICGFKIHGQNVPFDAVV
    VDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATV
    HIQVNDVNEYAPVFKEKSYKATVIEGKQYDSILRVEAVDADCSPQFSQIC
    SYEIITPDVPFTVDKDGYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATED
    VLVKISIKPTCTPGWQGWNNRIEYEPGTGALAVFPNIHLETCDEPVASVQ
    ATVELETSHIGKGCDRDTYSEKSLHRLCGAAAGTAELLPSPSGSLNWTMG
    LPTDNGHDSDQVFEFNGTQAVRIPDGVVSVSPKEPFTISVWMRHGPFGRK
    KETILCSSDKTDMNRHHYSLYVHGCRLIFLFRQDPSEEKKYRPAEFHWKL
    NQVCDEEWHHYVLNVEFPSVTLYVDGTSHEPFSVTEDYPLHPSKIETQLV
    VGACWQEFSGVENDNETEPVTVASAGGDLHMTQFFRGNLAGLTLRSGKLA
    DKKVIDCLYTCKEGLDLQVLEDSGRGVQIQAHPSQLVLTLEGEDLGELDK
    AMQHISYLNSRQFPTPGIRRLKITSTIKCFNEATCISVPPVDGYVMVLQP
    EEPKISLSGVHHFARAASEFESSEGVFLFPELRIISTITREVEPEGDGAE
    DPTVQESLVSEEIVHDLDTCEVTVEGEELNHEQESLEVDMARLQQKGIEV
    SSSELGMTFTGVDTMASYEEVLHLLRYRNWHARSLLDRKFKLICSELNGR
    YISNEFKVEVNVIHTANPMEHANHMAAQPQFVHPEHRSFVDLSGHNLANP
    HPFAVVPSTATVVIVVCVSFLVFMIILGVFRIRAAHRRTMRDQDTGKENE
    MDWDDSALTITVNPMETYEDQHSSEEEEEEEEEEESEDGEEEDDITSAES
    ESSEEEEGEQGDPQNATRQQQLEWDDSTLSY

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • CLSTN1
  • Full Name
  • Calsyntenin 1
  • Introduction
  • This gene is a member of the calsyntenin family, a subset of the cadherin superfamily. The encoded transmembrane protein, also known as alcadein-alpha, is thought to bind to kinesin-1 motors to mediate the axonal anterograde transport of certain types of vesicle. Amyloid precursor protein (APP) is trafficked via these vesicles and so this protein is being investigated to see how it might contribute to the mechanisms underlying Alzheimer's disease. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • CLSTN1; CST-1; CSTN1; CDHR12; PIK3CD; ALC-ALPHA; XB31alpha; alcalpha1; alcalpha2; calsyntenin-1; alcadein-alpha; alzheimer-related cadherin-like protein; cadherin-related family member 12; non-classical cadherin XB31alpha; Calsyntenin 1

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