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Magic™ Membrane Protein Human CNGA1 (Cyclic nucleotide gated channel subunit alpha 1) Full Length (CAT#: MPC1051K) Made to Order

This product is a 79.5 kDa Human CNGA1 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CNGA1
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 79.5 kDa
  • TMD
  • 6
  • Sequence
  • MKLSMKNNIINTQQSFVTMPNVIVPDIEKEIRRMENGACSSFSEDDDSAS
    TSEESENENPHARGSFSYKSLRKGGPSQREQYLPGAIALFNVNNSSNKDQ
    EPEEKKKKKKEKKSKSDDKNENKNDPEKKKKKKDKEKKKKEEKSKDKKEE
    EKKEVVVIDPSGNTYYNWLFCITLPVMYNWTMVIARACFDELQSDYLEYW
    LILDYVSDIVYLIDMFVRTRTGYLEQGLLVKEELKLINKYKSNLQFKLDV
    LSLIPTDLLYFKLGWNYPEIRLNRLLRFSRMFEFFQRTETRTNYPNIFRI
    SNLVMYIVIIIHWNACVFYSISKAIGFGNDTWVYPDINDPEFGRLARKYV
    YSLYWSTLTLTTIGETPPPVRDSEYVFVVVDFLIGVLIFATIVGNIGSMI
    SNMNAARAEFQARIDAIKQYMHFRNVSKDMEKRVIKWFDYLWTNKKTVDE
    KEVLKYLPDKLRAEIAINVHLDTLKKVRIFADCEAGLLVELVLKLQPQVY
    SPGDYICKKGDIGREMYIIKEGKLAVVADDGVTQFVVLSDGSYFGEISIL
    NIKGSKAGNRRTANIKSIGYSDLFCLSKDDLMEALTEYPDAKTMLEEKGK
    QILMKDGLLDLNIANAGSDPKDLEEKVTRMEGSVDLLQTRFARILAEYES
    MQQKLKQRLTKVEKFLKPLIDTEFSSIEGPGAESGPIDST

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • CNGA1
  • Full Name
  • Cyclic nucleotide gated channel subunit alpha 1
  • Introduction
  • The protein encoded by this gene is involved in phototransduction. Along with another protein, the encoded protein forms a cGMP-gated cation channel in the plasma membrane, allowing depolarization of rod photoreceptors. This represents the last step in the phototransduction pathway. Defects in this gene are a cause of retinitis pigmentosa autosomal recessive (ARRP) disease. Multiple transcript variants have been found for this gene.
  • Alternative Names
  • CNGA1; CNCG; CNG1; RP49; CNCG1; CNG-1; RCNC1; RCNCa; RCNCalpha; cGMP-gated cation channel alpha-1; CNG channel alpha-1; cyclic nucleotide gated channel alpha 1; cyclic nucleotide-gated cation channel 1; cyclic nucleotide-gated channel, photoreceptor; interleukin-1 homologue; rod photoreceptor cGMP-gated channel subunit alpha; Cyclic nucleotide-gated channel, photoreceptor; Cyclic nucleotide gated channel subunit alpha 1

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