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Magic™ Membrane Protein Human DSG3 (Desmoglein 3) Full Length (CAT#: MPC1769K) Made to Order

This product is a 107.5 kDa Human DSG3 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • DSG3
  • Protein Length
  • Full length
  • Protein Class
  • Cell adhesion
  • Molecular Weight
  • 107.5 kDa
  • TMD
  • 1
  • Sequence
  • MMGLFPRTTGALAIFVVVILVHGELRIETKGQYDEEEMTMQQAKRRQKRE
    WVKFAKPCREGEDNSKRNPIAKITSDYQATQKITYRISGVGIDQPPFGIF
    VVDKNTGDINITAIVDREETPSFLITCRALNAQGLDVEKPLILTVKILDI
    NDNPPVFSQQIFMGEIEENSASNSLVMILNATDADEPNHLNSKIAFKIVS
    QEPAGTPMFLLSRNTGEVRTLTNSLDREQASSYRLVVSGADKDGEGLSTQ
    CECNIKVKDVNDNFPMFRDSQYSARIEENILSSELLRFQVTDLDEEYTDN
    WLAVYFFTSGNEGNWFEIQTDPRTNEGILKVVKALDYEQLQSVKLSIAVK
    NKAEFHQSVISRYRVQSTPVTIQVINVREGIAFRPASKTFTVQKGISSKK
    LVDYILGTYQAIDEDTNKAASNVKYVMGRNDGGYLMIDSKTAEIKFVKNM
    NRDSTFIVNKTITAEVLAIDEYTGKTSTGTVYVRVPDFNDNCPTAVLEKD
    AVCSSSPSVVVSARTLNNRYTGPYTFALEDQPVKLPAVWSITTLNATSAL
    LRAQEQIPPGVYHISLVLTDSQNNRCEMPRSLTLEVCQCDNRGICGTSYP
    TTSPGTRYGRPHSGRLGPAAIGLLLLGLLLLLLAPLLLLTCDCGAGSTGG
    VTGGFIPVPDGSEGTIHQWGIEGAHPEDKEITNICVPPVTANGADFMESS
    EVCTNTYARGTAVEGTSGMEMTTKLGAATESGGAAGFATGTVSGAASGFG
    AATGVGICSSGQSGTMRTRHSTGGTNKDYADGAISMNFLDSYFSQKAFAC
    AEEDDGQEANDCLLIYDNEGADATGSPVGSVGCCSFIADDLDDSFLDSLG
    PKFKKLAEISLGVDGEGKEVQPPSKDSGYGIESCGHPIEVQQTGFVKCQT
    LSGSQGASALSTSGSVQPAVSIPDPLQHGNYLVTETYSASGSLVQPSTAG
    FDPLLTQNVIVTERVICPISSVPGNLAGPTQLRGSHTMLCTEDPCSRLI

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • DSG3
  • Full Name
  • Desmoglein 3
  • Introduction
  • This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. The encoded protein has been identified as the autoantigen of the autoimmune blistering disease pemphigus vulgaris.
  • Alternative Names
  • DSG3; PVA; ABOLM; CDHF6; desmoglein-3; 130 kDa pemphigus vulgaris antigen; cadherin family member 6; Desmoglein 3

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