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Magic™ Membrane Protein Human EPHB3 (EPH receptor B3) Expressed in NS0 for Antibody Discovery, Partial (38-550aa) (CAT#: MPX0185K)

Datasheet
This product is a 82.7 kDa Human EPHB3 membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • EPHB3
  • Protein Length
  • Partial (38-550aa)
  • Protein Class
  • Transferase
  • Molecular Weight
  • 82.7 kDa
  • TMD
  • 1
  • Sequence
  • LEETLMDTKWVTS
    ELAWTSHPESGWEEVSGYDEAMNPIRTYQVCNVRESSQNNWLRTGFIWRR
    DVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYEADSDVASASSPFWM
    ENPYVKVDTIAPDESFSRLDAGRVNTKVRSFGPLSKAGFYLAFQDQGACM
    SLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIPNAVEVSV
    PLKLYCNGDGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGP
    CLPCPPNSRTTSPAASICTCHNNFYRADSDSADSACTTVPSPPRGVISNV
    NETSLILEWSEPRDLGGRDDLLYNVICKKCHGAGGASACSRCDDNVEFVP
    RQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPLPPRYAAVNITTNQ
    AAPSEVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEKSEGIAST
    VTSQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEFETTSERGSGA

Product Description

  • Expression Systems
  • NS0
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 200 μg/mL in PBS.
  • Endotoxin
  • <0.01 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • EPHB3
  • Full Name
  • EPH receptor B3
  • Introduction
  • Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into two groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. This gene encodes a receptor for ephrin-B family members.
  • Alternative Names
  • EPHB3; EK2; ETK2; HEK2; TYRO6; ephrin type-B receptor 3; EPH-like tyrosine kinase 2; embryonic kinase 2; human embryo kinase 2; tyrosine-protein kinase TYRO6; EPH receptor B3

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