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Magic™ Membrane Protein Human EPHB6 (EPH receptor B6) Expressed in NS0 for Antibody Discovery, Partial (17-579aa) (CAT#: MPX0303K)

Datasheet
This product is a 86.7 kDa Human EPHB6 membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • EPHB6
  • Protein Length
  • Partial (17-579aa)
  • Protein Class
  • Receptor
  • Molecular Weight
  • 86.7 kDa
  • TMD
  • 1
  • Sequence
  • VCSLWVLLLVSSVLALEEVLLDTTGETSEIGWLT
    YPPGGWDEVSVLDDQRRLTRTFEACHVAGAPPGTGQDNWLQTHFVERRGA
    QRAHIRLHFSVRACSSLGVSGGTCRETFTLYYRQAEEPDSPDSVSSWHLK
    RWTKVDTIAADESFPSSSSSSSSSSSAAWAVGPHGAGQRAGLQLNVKERS
    FGPLTQRGFYVAFQDTGACLALVAVRLFSYTCPAVLRSFASFPETQASGA
    GGASLVAAVGTCVAHAEPEEDGVGGQAGGSPPRLHCNGEGKWMVAVGGCR
    CQPGYQPARGDKACQACPRGLYKSSAGNAPCSPCPARSHAPNPAAPVCPC
    LEGFYRASSDPPEAPCTGPPSAPQELWFEVQGSALMLHWRLPRELGGRGD
    LLFNVVCKECEGRQEPASGGGGTCHRCRDEVHFDPRQRGLTESRVLVGGL
    RAHVPYILEVQAVNGVSELSPDPPQAAAINVSTSHEVPSAVPVVHQVSRA
    SNSITVSWPQPDQTNGNILDYQLRYYDQAEDESHSFTLTSETNTATVTQL
    SPGHIYGFQVRARTAAGHGPYGGKVYFQT

Product Description

  • Expression Systems
  • NS0
  • Tag
  • hIgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 100 μg/mL in sterile PBS.
  • Endotoxin
  • <0.01 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • EPHB6
  • Full Name
  • EPH receptor B6
  • Introduction
  • This gene encodes a member of a family of transmembrane proteins that function as receptors for ephrin-B family proteins. Unlike other members of this family, the encoded protein does not contain a functional kinase domain. Activity of this protein can influence cell adhesion and migration. Expression of this gene is downregulated during tumor progression, suggesting that the protein may suppress tumor invasion and metastasis. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • EPHB6; HEP; ephrin type-B receptor 6; human kinase-defective Eph-family receptor protein; tyrosine-protein kinase-defective receptor EPH-6; EPH receptor B6

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