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Magic™ Membrane Protein Human GET1 (Guided entry of tail-anchored proteins factor 1) for Antibody Discovery (CAT#: MP1500X)

Datasheet
This product is a 46.2 kDa Human GET1 membrane protein expressed in In vitro wheat germ expression system with proprietary liposome technology. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GET1
  • Protein Length
  • Full-length
  • Molecular Weight
  • 46.2 kDa
  • TMD
  • 3
  • Sequence
  • MSSAAADHWAWLLVLSFVFGCNVLRILLPSFSSFMSRVLQKDAEQESQMRAEIQDMKQELSTVNMMDEFARYARLERKINKMTDKLKTHVKARTAQLAKIKWVISVAFYVLQAALMISLIWKYYSVPVAVVPSKWITPLDRLVAFPTRVAGGVGITCWILVCNKVVAIVLHPFS

Product Description

  • Application
  • Enzyme-linked Immunoabsorbent Assay, Western Blot (Recombinant protein), Antibody Production, Protein Array
  • Expression Systems
  • In vitro wheat germ expression system with proprietary liposome technology
  • Tag
  • GST-tag at N-terminal
  • Purification
  • Glutathione Sepharose 4 Fast Flow
  • Buffer
  • 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0

Target

  • Target Protein
  • GET1
  • Full Name
  • Guided entry of tail-anchored proteins factor 1
  • Introduction
  • This gene is located in the candidate region for congenital heart disease (CHD) in Down syndrome (DS). It encodes a basic protein that functions as a receptor that promotes insertion of tail-anchored proteins in the endoplasmic reticulum membrane. This gene is located at a maternally-methylated differentially methylated region (DMR); however, its transcription may be biallelic, not imprinted. Alternative splicing results in different transcript variants. A pseudogene has been defined on chromosome 4.
  • Alternative Names
  • WRB; CHD5; guided entry of tail-anchored proteins factor 1; congenital heart disease 5 protein; tail-anchored protein insertion receptor WRB; tryptophan rich basic protein

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