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Magic™ Membrane Protein Human GPER1 (G protein-coupled estrogen receptor 1) Full Length (CAT#: MPC0330K) Made to Order

Datasheet
This product is a 42.2 kDa Human GPER1 membrane protein expressed in Baculovirus/Insect expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GPER1
  • Protein Length
  • Full length
  • Protein Class
  • GPCR
  • Molecular Weight
  • 42.2 kDa
  • TMD
  • 7
  • Sequence
  • MDVTSQARGVGLEMYPGTAQPAAPNTTSPELNLSHPLLGTALANGTGELS
    EHQQYVIGLFLSCLYTIFLFPIGFVGNILILVVNISFREKMTIPDLYFIN
    LAVADLILVADSLIEVFNLHERYYDIAVLCTFMSLFLQVNMYSSVFFLTW
    MSFDRYIALARAMRCSLFRTKHHARLSCGLIWMASVSATLVPFTAVHLQH
    TDEACFCFADVREVQWLEVTLGFIVPFAIIGLCYSLIVRVLVRAHRHRGL
    RPRRQKALRMILAVVLVFFVCWLPENVFISVHLLQRTQPGAAPCKQSFRH
    AHPLTGHIVNLAAFSNSCLNPLIYSFLGETFRDKLRLYIEQKTNLPALNR
    FCHAALKAVIPDSTEQSDVRFSSAV

Product Description

  • Expression Systems
  • Baculovirus/Insect expression system
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • GPER1
  • Full Name
  • G protein-coupled estrogen receptor 1
  • Introduction
  • This gene encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum and a member of the G-protein coupled receptor 1 family. This receptor binds estrogen and activates multiple downstream signaling pathways, leading to stimulation of adenylate cyclase and an increase in cyclic AMP levels, while also promoting intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. This receptor has been shown to play a role in diverse biological processes, including bone and nervous system development, metabolism, cognition, male fertility and uterine function.
  • Alternative Names
  • mER; CEPR; GPER; DRY12; FEG-1; GPR30; LERGU; LyGPR; CMKRL2; LERGU2; GPCR-Br; G-protein coupled estrogen receptor 1; G protein-coupled receptor 30; IL8-related receptor DRY12; chemoattractant receptor-like 2; chemokine receptor-like 2; constitutively expressed peptide-like receptor; flow-induced endothelial G-protein coupled receptor 1; heptahelix receptor; lymphocyte-derived G-protein coupled receptor; membrane estrogen receptor; GPER1; G protein-coupled estrogen receptor 1

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