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Magic™ Membrane Protein Human GRIK3 (Glutamate ionotropic receptor kainate type subunit 3) Full Length (CAT#: MPC0563K) Made to Order

Datasheet
This product is a 104 kDa Human GRIK3 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GRIK3
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 104 kDa
  • TMD
  • 3
  • Sequence
  • MTAPWRRLRSLVWEYWAGLLVCAFWIPDSRGMPHVIRIGGIFEYADGPNA
    QVMNAEEHAFRFSANIINRNRTLLPNTTLTYDIQRIHFHDSFEATKKACD
    QLALGVVAIFGPSQGSCTNAVQSICNALEVPHIQLRWKHHPLDNKDTFYV
    NLYPDYASLSHAILDLVQYLKWRSATVVYDDSTGLIRLQELIMAPSRYNI
    RLKIRQLPIDSDDSRPLLKEMKRGREFRIIFDCSHTMAAQILKQAMAMGM
    MTEYYHFIFTTLDLYALDLEPYRYSGVNLTGFRILNVDNPHVSAIVEKWS
    MERLQAAPRSESGLLDGVMMTDAALLYDAVHIVSVCYQRAPQMTVNSLQC
    HRHKAWRFGGRFMNFIKEAQWEGLTGRIVFNKTSGLRTDFDLDIISLKED
    GLEKVGVWSPADGLNITEVAKGRGPNVTDSLTNRSLIVTTVLEEPFVMFR
    KSDRTLYGNDRFEGYCIDLLKELAHILGFSYEIRLVEDGKYGAQDDKGQW
    NGMVKELIDHKADLAVAPLTITHVREKAIDFSKPFMTLGVSILYRKPNGT
    NPSVFSFLNPLSPDIWMYVLLAYLGVSCVLFVIARFSPYEWYDAHPCNPG
    SEVVENNFTLLNSFWFGMGSLMQQGSELMPKALSTRIIGGIWWFFTLIII
    SSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVKDGATMTFFKKSK
    ISTFEKMWAFMSSKPSALVKNNEEGIQRALTADYALLMESTTIEYVTQRN
    CNLTQIGGLIDSKGYGIGTPMGSPYRDKITIAILQLQEEDKLHIMKEKWW
    RGSGCPEEENKEASALGIQKIGGIFIVLAAGLVLSVLVAVGEFVYKLRKT
    AEREQRSFCSTVADEIRFSLTCQRRVKHKPQPPMMVKTDAVINMHTFNDR
    RLPGKDSMACSTSLAPVFP

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • GRIK3
  • Full Name
  • Glutamate ionotropic receptor kainate type subunit 3
  • Introduction
  • Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics.
  • Alternative Names
  • EAA5; GLR7; GLUR7; GluK3; GluR7a; glutamate receptor ionotropic, kainate 3; dJ1090M5.1 (glutamate receptor, ionotropic, kainate 3 (GLUR7)); excitatory amino acid receptor 5; gluR-7; glutamate receptor 7; GRIK3; Glutamate ionotropic receptor kainate type subunit 3

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