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Magic™ Membrane Protein Human HS2ST1 (Heparan sulfate 2-O-sulfotransferase 1) Expressed in CHO for Antibody Discovery, Partial (59-356aa) (CAT#: MPX0800K)

Datasheet
This product is a 36 kDa Human HS2ST1 membrane protein expressed in CHO. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • HS2ST1
  • Protein Length
  • Partial (59-356aa)
  • Protein Class
  • Transferase
  • Molecular Weight
  • 36 kDa
  • TMD
  • 1
  • Sequence
  • MDGPRQDATLDEEEDMVIIYNRVPKTASTSFTNIAYDLCAKN
    KYHVLHINTTKNNPVMSLQDQVRFVKNITSWKEMKPGFYHGHVSYLDFAK
    FGVKKKPIYINVIRDPIERLVSYYYFLRFGDDYRPGLRRRKQGDKKTFDE
    CVAEGGSDCAPEKLWLQIPFFCGHSSECWNVGSRWAMDQAKYNLINEYFL
    VGVTEELEDFIMLLEAALPRFFRGATELYRTGKKSHLRKTTEKKLPTKQT
    IAKLQQSDIWKMENEFYEFALEQFQFIRAHAVREKDGDLYILAQNFFYEK
    IYPKSN

Product Description

  • Activity
  • Yes
  • Expression Systems
  • CHO
  • Tag
  • 6xHis tag at the N-terminus
  • Protein Format
  • Soluble
  • Endotoxin
  • <1.0 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >90%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain at 5 μg per lane.
  • Buffer
  • Supplied as a 0.2 μm filtered solution in Tris and NaCl.

Target

  • Target Protein
  • HS2ST1
  • Full Name
  • Heparan sulfate 2-O-sulfotransferase 1
  • Introduction
  • Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. This gene encodes a member of the heparan sulfate biosynthetic enzyme family that transfers sulfate to the 2 position of the iduronic acid residue of heparan sulfate. The disruption of this gene resulted in no kidney formation in knockout embryonic mice, indicating that the absence of this enzyme may interfere with the signaling required for kidney formation. Two alternatively spliced transcript variants that encode different proteins have been found for this gene.
  • Alternative Names
  • HS2ST1; NFSRA; dJ604K5.2; 2-O-sulfotransferase; 2OST; Heparan sulfate 2-O-sulfotransferase 1

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