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Magic™ Membrane Protein Human HTR3D (5-hydroxytryptamine receptor 3D) Full Length (CAT#: MPC1996K) Made to Order

Datasheet
This product is a 50.1 kDa Human HTR3D membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • HTR3D
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 50.1 kDa
  • TMD
  • 4
  • Sequence
  • MQKHSPGPPALALLSQSLLTTGNGDTLIINCPGFGQHRVDPAAFQAVFDR
    KAIGPVTNYSVATHVNISFTLSAIWNCYSRIHTFNCHHARPWHNQFVQWN
    PDECGGIKKSGMATENLWLSDVFIEESVDQTPAGLMASMSIVKATSNTIS
    QCGWSASANWTPSISPSMDRARAWRRMSRSFQIHHRTSFRTRREWVLLGI
    QKRTIKVTVATNQYEQAIFHVAIRRRCRPSPYVVNFLVPSGILIAIDALS
    FYLPLESGNCAPFKMTVLLGYSVFLLMMNDLLPATSTSSHASLVAPLALM
    QTPLPAGVYFALCLSLMVGSLLETIFITHLLHVATTQPLPLPRWLHSLLL
    HCTGQGRCCPTAPQKGNKGPGLTPTHLPGVKEPEVSAGQMPGPGEAELTG
    GSEWTRAQREHEAQKQHSVELWVQFSHAMDALLFRLYLLFMASSIITVIC
    LWNT

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • HTR3D
  • Full Name
  • 5-hydroxytryptamine receptor 3D
  • Introduction
  • The protein encoded this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit D of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a mitogen and a hormone. This hormone has been linked to neuropsychiatric disorders, including anxiety, depression, and migraine. Serotonin receptors causes fast and depolarizing responses in neurons following activation. The genes encoding subunits C, D and E of this type 3 receptor form a cluster on chromosome 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • HTR3D; 5HT3D; 5-hydroxytryptamine (serotonin) receptor 3 family member D; 5-hydroxytryptamine (serotonin) receptor 3D, ionotropic; 5-hydroxytryptamine receptor 3 subunit D; serotonin 5-HT-3D receptor; serotonin receptor 3D; 5-hydroxytryptamine receptor 3D

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