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Magic™ Membrane Protein Human ICAM5 (Intercellular adhesion molecule 5) Expressed in NS0 for Antibody Discovery, Partial (28-570aa) (CAT#: MPX0493K)

Datasheet
This product is a 85.1 kDa Human ICAM5 membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ICAM5
  • Protein Length
  • Partial (28-570aa)
  • Protein Class
  • Cell adhesion
  • Molecular Weight
  • 85.1 kDa
  • TMD
  • 1
  • Sequence
  • AVSQEPFWADLQPRVAFVERGGS
    LWLNCSTNCPRPERGGLETSLRRNGTQRGLRWLARQLVDIREPETQPVCF
    FRCARRTLQARGLIRTFQRPDRVELMPLPPWQPVGENFTLSCRVPGAGPR
    ASLTLTLLRGAQELIRRSFAGEPPRARGAVLTATVLARREDHGANFSCRA
    ELDLRPHGLGLFENSSAPRELRTFSLSPDAPRLAAPRLLEVGSERPVSCT
    LDGLFPASEARVYLALGDQNLSPDVTLEGDAFVATATATASAEQEGARQL
    VCNVTLGGENRETRENVTIYSFPAPLLTLSEPSVSEGQMVTVTCAAGAQA
    LVTLEGVPAAVPGQPAQLQLNATENDDRRSFFCDATLDVDGETLIKNRSA
    ELRVLYAPRLDDSDCPRSWTWPEGPEQTLRCEARGNPEPSVHCARSDGGA
    VLALGLLGPVTRALSGTYRCKAANDQGEAVKDVTLTVEYAPALDSVGCPE
    RITWLEGTEASLSCVAHGVPPPDVICVRSGELGAVIEGLLRVAREHAGTY
    RCEATNPRGSAAKNVAVTVE

Product Description

  • Activity
  • Yes
  • Expression Systems
  • NS0
  • Tag
  • hIgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 400 μg/mL in sterile PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • ICAM5
  • Full Name
  • Intercellular adhesion molecule 5
  • Introduction
  • The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases.
  • Alternative Names
  • ICAM5; TLN; TLCN; ICAM-5; intercellular adhesion molecule 5, telencephalin; telencephalin; Intercellular adhesion molecule 5

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