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Magic™ Membrane Protein Human ICMT (Isoprenylcysteine carboxyl methyltransferase) Full Length (CAT#: MPC4192K) Made to Order

This product is a made-to-order Human ICMT membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ICMT
  • Protein Length
  • Full length
  • Protein Class
  • Transferase
  • TMD
  • 8
  • Sequence
  • MAGCAARAPPGSEARLSLATFLLGASVLALPLLTRAGLQGRTGLALYVAG
    LNALLLLLYRPPRYQIAIRACFLGFVFGCGTLLSFSQSSWSHFGWYMCSL
    SLFHYSEYLVTAVNNPKSLSLDSFLLNHSLEYTVAALSSWLEFTLENIFW
    PELKQITWLSVTGLLMVVFGECLRKAAMFTAGSNFNHVVQNEKSDTHTLV
    TSGVYAWFRHPSYVGWFYWSIGTQVMLCNPICGVSYALTVWRFFRDRTEE
    EEISLIHFFGEEYLEYKKRVPTGLPFIKGVKVDL

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • ICMT
  • Full Name
  • Isoprenylcysteine carboxyl methyltransferase
  • Introduction
  • This gene encodes the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined.
  • Alternative Names
  • ICMT; PCMT; PPMT; PCCMT; HSTE14; MST098; MSTP098; protein-S-isoprenylcysteine O-methyltransferase; prenylated protein carboxyl methyltransferase; prenylcysteine carboxyl methyltransferase; Isoprenylcysteine carboxyl methyltransferase

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