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Magic™ Membrane Protein Human IL10RA (Interleukin 10 receptor subunit alpha) Expressed in Yeast with 10xHis tag at the N-terminus, Myc tag at the C-terminus for Antibody Discovery, Partial (22-235aa) (CAT#: MPX4169K)

Datasheet
This product is a 28.7 kDa Human IL10RA membrane protein expressed in Yeast. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • IL10RA
  • Protein Length
  • Partial (22-235aa)
  • Protein Class
  • Receptor
  • Molecular Weight
  • 28.7 kDa
  • TMD
  • 1
  • Sequence
  • HGTELPSPPSVWFEAEFFHHILHWTPIPNQSESTCYEVALLRYGIESWNSISNCSQTLSYDLTAVTLDLYHSNGYRARVRAVDGSRHSNWTVTNTRFSVDEVTLTVGSVNLEIHNGFILGKIQLPRPKMAPANDTYESIFSHFREYEIAIRKVPGNFTFTHKKVKHENFSLLTSGEVGEFCVQVKPSVASRSNKGMWSKEECISLTRQYFTVTN

Product Description

  • Expression Systems
  • Yeast
  • Tag
  • 10xHis tag at the N-terminus, Myc tag at the C-terminus
  • Protein Format
  • Soluble
  • Purity
  • >85% as determined by SDS-PAGE.
  • Buffer
  • Tris/PBS-based buffer, 6% Trehalose, pH 8.0

Target

  • Target Protein
  • IL10RA
  • Full Name
  • Interleukin 10 receptor subunit alpha
  • Introduction
  • The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.
  • Alternative Names
  • IL10RA; CD210; IL10R; CD210a; CDW210A; HIL-10R; IL-10R1; IL-10 receptor subunit alpha; IL-10R subunit 1; IL-10R subunit alpha; IL-10RA; interleukin 10 receptor, alpha; interleukin-10 receptor alpha chain; interleukin-10 receptor subunit 1; Interleukin 10 receptor subunit alpha

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