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Magic™ Membrane Protein Human IL17RC (Interleukin 17 receptor C) Full Length (CAT#: MPC2465K) Made to Order

Datasheet
This product is a made-to-order Human IL17RC membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • IL17RC
  • Protein Length
  • Full length
  • Protein Class
  • Receptor
  • TMD
  • 1
  • Sequence
  • MPVPWFLLSLALGRSPVVLSLERLVGPQDATHCSPVSLEPWGDEERLRVQ
    FLAQQSLSLAPVTAATARTALSGLSGADGRREERGRGKSWVCLSLGGSGN
    TEPQKKGLSCRLWDSDILCLPGDIVPAPGPVLAPTHLQTELVLRCQKETD
    CDLCLRVAVHLAVHGHWEEPEDEEKFGGAADSGVEEPRNASLQAQVVLSF
    QAYPTARCVLLEVQVPAALVQFGQSVGSVVYDCFEAALGSEVRIWSYTQP
    RYEKELNHTQQLPDCRGLEVWNSIPSCWALPWLNVSADGDNVHLVLNVSE
    EQHFGLSLYWNQVQGPPKPRWHKNLTGPQIITLNHTDLVPCLCIQVWPLE
    PDSVRTNICPFREDPRAHQNLWQAARLQLLTLQSWLLDAPCSLPAEAALC
    WRAPGGDPCQPLVPPLSWENVTVDKVLEFPLLKGHPNLCVQVNSSEKLQL
    QECLWADSLGPLKDDVLLLETRGPQDNRSLCALEPSGCTSLPSKASTRAA
    RLGEYLLQDLQSGQCLQLWDDDLGALWACPMDKYIHKRWALVWLACLLFA
    AALSLILLLKKDHAKGWLRLLKQDVRSGAAARGRAALLLYSADDSGFERL
    VGALASALCQLPLRVAVDLWSRRELSAQGPVAWFHAQRRQTLQEGGVVVL
    LFSPGAVALCSEWLQDGVSGPGAHGPHDAFRASLSCVLPDFLQGRAPGSY
    VGACFDRLLHPDAVPALFRTVPVFTLPSQLPDFLGALQQPRAPRSGRLQE
    RAEQVSRALQPALDSYFHPPGTPAPGRGVGPGAGPGAGDGT

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • IL17RC
  • Full Name
  • Interleukin 17 receptor C
  • Introduction
  • This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling.
  • Alternative Names
  • IL17RC; CANDF9; IL17RL; IL17-RL; interleukin-17 receptor C; IL-17 receptor C; IL-17RL; IL17F receptor; IL17Rhom; interleukin-17 receptor homolog; interleukin-17 receptor-like protein; zcytoR14; Interleukin 17 receptor C

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